DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Vsig10

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001258265.1	Gene:	Vsig10 / 304529	RGDID:	1565800	Length:	564	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	75/318 - (23%)
Similarity:	124/318 - (38%)	Gaps:	65/318 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 ISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIH 154
            ||:.|      .:|...:..|:|....|:|.           ..:..|.:|.|       .:..|
  Rat   156 ISATG------TLPNGTLYAARGSQVDFSCC-----------SAAQPPPEVEW-------WIQTH 196

  Fly   155 EHVITN-NDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQ-VNTDPMKMQTATLEVVI--PPDIIN 215
            ..|..: ...||.     |::||.:....::  |.|.|. .|....:.:..|.|:::  ||....
  Rat   197 SSVSESLGKNLSA-----NSFTLMLMSKNLQ--GNYTCSATNVLSRRQRKVTTELLVYWPPPSAP 254

  Fly   216 EETSGDMMVPEGGSAKLVCR-ARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKI 279
            :.::|  :.||..:.:|.|. ..|:|.|...|..|.|..::..:             ::.|||..
  Rat   255 QCSAG--LSPESANLELTCNWDGGYPDPTFLWTEEPGGVVVGNS-------------KLQTLSPS 304

  Fly   280 TRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQ--LVGAPVLTDVTLICNVE-ASPKAI 341
            ..||...:.|:.|:.:.|.......:|:....|...|.:  |||.    ||||.|.|| |:|.|.
  Rat   305 QLSEGKKFKCVGSHILGPESGASCVVQISSPLLASRPMKTCLVGG----DVTLTCQVEGANPPAR 365

  Fly   342 NYWQR---ENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIG 396
            ..|.|   :....|....||.:|::..:.   .:.:| ...|..|.|.|.|.::|.:|
  Rat   366 IQWLRNLTQPETAIQPSSRYVITQQGQSS---SLTIH-NCSQDQDGGFYFCRAENPVG 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	21/112 (19%)
		ig	102..195	CDD:278476	18/94 (19%)
		IG_like	219..307	CDD:214653	19/88 (22%)
		Ig	221..307	CDD:299845	18/86 (21%)
		Ig	311..404	CDD:299845	29/92 (32%)
		IG_like	327..405	CDD:214653	24/74 (32%)
Vsig10	NP_001258265.1	Ig	60..146	CDD:299845
		IG_like	60..145	CDD:214653
		IG_like	165..246	CDD:214653	20/105 (19%)
		Ig	175..241	CDD:143165	16/90 (18%)
		Ig_3	255..318	CDD:290638	17/77 (22%)
		IG_like	347..429	CDD:214653	26/81 (32%)
		Ig	351..426	CDD:143165	23/73 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010