DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Tapbpl

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001100092.1	Gene:	Tapbpl / 297602	RGDID:	1307893	Length:	446	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	70/338 - (20%)
Similarity:	125/338 - (36%)	Gaps:	77/338 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LVVKESGERIADISCSQEHTT----KFSPKLSQVAKHRK----LAQLEIASGSGLVGLGTGTGTG 61
            ||.....|.:....||.:..|    ::..:..|.|...|    ::.::::.|...|.:...|...
  Rat   101 LVQIPQAEALLHADCSGKAVTCEIAQYFLQARQEATFEKADWFISNMQVSRGGPSVSIVMKTLRD 165

  Fly    62 SGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQ--GRDATFTCVVNNL 124
            ...| |:|...|.:.|....   ||..|:        :|.:..|..|:.|  |...:..|..:..
  Rat   166 DEAG-AVRHPSLNIPLSPQG---TVKTKV--------EFQVTAETQTLNQLLGSSVSLPCRFSMA 218

  Fly   125 GG-----------HRVSGD--------GSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQHND 170
            .|           |:.||.        ...|..|.|.:|.         |.::...|.
  Rat   219 PGLDLTGVEWRLQHKGSGQLVYSWKTGQGQAKRKGATLKP---------EKLLRAGDA------- 267

  Fly   171 YNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCR 235
                :|.:..:.::|.|.|:||::|...:.|.     ::|.:|:.......::..:.....|:|.
  Rat   268 ----SLTLPNLTLKDEGNYICQISTSLYQAQQ-----IVPLNILASPKVQLILANKDPLPSLICS 323

  Fly   236 ARG-HP-KPKITWRREDGREIIAR-NGSHQKTKAQSVEGEMLTLSKITRSEMG----AYMCIASN 293
            ..| :| ...:||.||:...|.|: :|:...:..|::.|.....|.:| :|.|    .|.|..::
  Rat   324 IAGYYPLDVVVTWIREELGGIPAQVSGASFSSLRQNMMGTYSISSTVT-AEPGPTGATYTCQVAH 387

  Fly   294 ---GVPPTVSKRM 303
               ..|.|||.|:
  Rat   388 VSLEEPLTVSMRV 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	24/131 (18%)
		ig	102..195	CDD:278476	21/113 (19%)
		IG_like	219..307	CDD:214653	24/95 (25%)
		Ig	221..307	CDD:299845	24/93 (26%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
Tapbpl	NP_001100092.1	V-set	205..302	CDD:284989	21/121 (17%)
		IG_like	205..301	CDD:214653	21/120 (18%)
		Ig	267..397	CDD:299845	31/146 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000