DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Psg29

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001020812.1	Gene:	Psg29 / 292666	RGDID:	1565741	Length:	468	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	81/383 - (21%)
Similarity:	124/383 - (32%)	Gaps:	115/383 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LLLGNCIDLTVSNK--ISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPA 138
            :.|.||..|..|::  |.|:....|:                          ||.|:......|.
  Rat   138 VFLWNCGRLVTSSQPIIESLPHIVPE--------------------------GHHVALHVHKIPE 176

  Fly   139 KV---AWIKADAKAILAIHEHVITNNDRLSVQHNDY-----NTWTLN------IRGVKMEDAGKY 189
            .:   .|.|.     :.:..|:.....::|.:.:.:     ...|||      |..|...|||.|
  Rat   177 NIQGFIWFKG-----MTVFRHLEIVRYKMSSKSSVFGPAYSGRETLNSDGALLIENVTQTDAGLY 236

  Fly   190 MCQVNTDPMKMQTATLEV-VIPPDI--INEETSGDMMV-------PEGGSAKLVCRARGHPKPK- 243
            ..:|....||.:.|.:|: |..|..  .|..||...||       .:|.|..|:.    |..||
  Rat   237 TLRVLGTDMKSEEAHVEIRVEKPSFQCCNPITSSKFMVEAVPRYAAKGESVLLLV----HNLPKE 297

  Fly   244 ---ITW----RREDGREIIARN--------GSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASN 293
               .||    .|....:|:..:        |:..:.:........|.|..:|..:...|.....|
  Rat   298 LISFTWYNSMYRVSAFQIVNYHVIWNITTWGNEYRERGMVYANGSLLLQDVTEEDSRMYTLETLN 362

  Fly   294 GVPPTVSKRMKLQVHFH-------PLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEM 351
             |..||.   :..|.|:       |.|::.:..|.|.  ..||..| :.........|...|
  Rat   363 -VNYTVE---RAHVQFYVTKPVTQPFVRITDTTVNAH--RSVTFTC-ITPDVGIPTLWLFNN--- 417

  Fly   352 IIAGDRYALTEKENNMYAIEMI--------LHIKRLQSSDFGGYKCISKNSIGDTEGT 401
                         :|:...|.|        |.|..::|.|.|.|:|:..|..|||:.:
  Rat   418 -------------HNLQVTERIKMSPTKCGLRIDNVRSEDAGEYQCMVTNRAGDTKAS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	23/125 (18%)
		ig	102..195	CDD:278476	18/106 (17%)
		IG_like	219..307	CDD:214653	22/110 (20%)
		Ig	221..307	CDD:299845	21/108 (19%)
		Ig	311..404	CDD:299845	23/99 (23%)
		IG_like	327..405	CDD:214653	19/83 (23%)
Psg29	NP_001020812.1	Ig_CEACAM_D1	36..136	CDD:143251
		Ig_CEACAM_D1	152..256	CDD:143251	25/134 (19%)
		Ig	272..376	CDD:299845	23/111 (21%)
		IG_like	389..462	CDD:214653	21/91 (23%)
		IGc2	396..457	CDD:197706	16/77 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000