DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-beta and Ncam2

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:328 Identity:88/328 - (26%)
Similarity:138/328 - (42%) Gaps:83/328 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 PDFVIPLE--NVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITN 160
            |..|:|.:  |.|..:|.:.|.||          ...||..|| ::|.:                
  Rat   209 PAIVMPQKSFNATAERGEEMTLTC----------KASGSPDPA-ISWFR---------------- 246

  Fly   161 NDRLSVQHNDY-----NTWTLNIRGVKMEDAGKYMCQ-VNTDPMKMQTATLEVVIPPDII---NE 216
            |.:|..::..|     || .|.:|.:..:|.|.|:|: .|......:.|.|:|.:.|.|:   ||
  Rat   247 NGKLIEENEKYILKGSNT-ELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNE 310

  Fly   217 ETSGDMMVPEGGSAKLVCRARGHPKPKITWRR-------------EDGREIIARNGSHQKTKAQS 268
            .||      |.|...|:|.|.|.|.|:|||:|             .|||  |...|.|.::.   
  Rat   311 TTS------ENGHVTLICEAEGEPVPEITWKRAIDGVTFSEGDKSPDGR--IEVKGQHGRSS--- 364

  Fly   269 VEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLV-----GAPVLTDV 328
                 |.:..:..|:.|.|.|.|::.:... .:.|.|.:.:.|.. |.||.:     |.|    :
  Rat   365 -----LHIRDVKLSDSGRYDCEAASRIGGH-QRSMHLDIEYAPKF-VSNQTMYYSWEGNP----I 418

  Fly   329 TLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKN 393
            .:.|:|:|:|.|..:|:||  ::::....  .|..:.:....:|||.|.....:|||.|.|.:.|
  Rat   419 NISCDVKANPPASIHWRRE--KLVLPAKN--TTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATN 479

  Fly   394 SIG 396
            .||
  Rat   480 RIG 482

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352 29/118 (25%)
ig 102..195 CDD:278476 23/100 (23%)
IG_like 219..307 CDD:214653 27/100 (27%)
Ig 221..307 CDD:299845 26/98 (27%)
Ig 311..404 CDD:299845 27/91 (30%)
IG_like 327..405 CDD:214653 21/70 (30%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706
Ig strand B 130..139 CDD:409353
Ig strand C 145..153 CDD:409353
Ig strand C' 156..159 CDD:409353
Ig strand D 162..167 CDD:409353
Ig strand E 168..175 CDD:409353
IgI_1_MuSK 209..298 CDD:409562 28/116 (24%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 1/4 (25%)
Ig strand E 264..268 CDD:409562 2/4 (50%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 0/2 (0%)
Ig 300..397 CDD:416386 32/113 (28%)
Ig strand A 300..305 CDD:409353 1/4 (25%)
Ig strand A' 309..313 CDD:409353 2/3 (67%)
Ig strand B 317..325 CDD:409353 2/7 (29%)
Ig strand C 331..337 CDD:409353 3/5 (60%)
Ig strand C' 340..343 CDD:409353 0/2 (0%)
Ig strand D 353..359 CDD:409353 2/7 (29%)
Ig strand E 362..368 CDD:409353 1/13 (8%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 2/10 (20%)
Ig_3 401..479 CDD:404760 24/86 (28%)
Ig strand B 418..422 CDD:409353 0/3 (0%)
Ig strand C 431..435 CDD:409353 0/3 (0%)
Ig strand E 458..462 CDD:409353 3/3 (100%)
Ig strand F 472..477 CDD:409353 2/4 (50%)
Ig strand G 486..489 CDD:409353
FN3 496..588 CDD:238020
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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