DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Psg18

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_036093.2	Gene:	Psg18 / 26438	MGIID:	1347251	Length:	476	Species:	Mus musculus

Alignment Length:	440	Identity:	94/440 - (21%)
Similarity:	145/440 - (32%)	Gaps:	154/440 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VKESGERIADIS-----------CSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGT 60
            :.:.||.:::.|           |.:. ||..||.:       :|....:|:|
Mouse   125 ISKRGEIVSNTSLYLHVYSSLFICVRP-TTLISPTI-------ELVPASVAAG------------ 169

  Fly    61 GSGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLG 125
            ||           :|||:.|     :...:.|:  |....:|....|.||:.|.|
Mouse   170 GS-----------ILLLVHN-----IPKYLQSL--FWYKGLIAFNKVEIARYRTA---------- 206

  Fly   126 GHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDRL--SVQHNDYNTWTLN--IRGVKMEDA 186
                ...|...||...            .|.|.:|...|  :|...|...:||.  .|..|||.|
Mouse   207 ----KNSGEPGPAHSG------------RETVYSNGSLLLQNVTWKDTGFYTLRTLTRYQKMEFA 255

  Fly   187 GKYM---------------CQVNTDPMKMQTA-----TLEV-VIPPDIINEE------TSGDMMV 224
            ..|:               .|::.||:....|     .|:| .:|.|:....      ::.|..:
Mouse   256 HIYLQVDTSHSLCCDTLDSAQLSIDPVPRHAAEGGSVLLQVHNLPEDVQTFSWYKGVLSTQDFKI 320

  Fly   225 PEGGSA-KLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYM 288
            .|...| |.:.|.|.|.:          |||...|||             |.|..:|..:.|.|.
Mouse   321 AEYSIATKSIIRGRAHSR----------REIGYTNGS-------------LLLQDVTEKDSGLYT 362

  Fly   289 CIASNGVPPTVSKRMK-----LQVHFHPLVQVPNQLV---GAPVLTDVTLICNVEASPKAINYWQ 345
            .|       |:...::     :||:.|.||..|...|   ...|.:.|...|..:.:..:|. |.
Mouse   363 LI-------TIDSNVRVVTAHVQVNIHQLVTQPAMRVTDSTVRVQSSVVFTCFSDNTGVSIR-WL 419

  Fly   346 RENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSI 395
            ..|       .|..|||: ..:...:..|.|..::..|.|.|:|.:.|.:
Mouse   420 FNN-------QRLQLTER-MTLSPSKCQLRIHTVRKEDAGEYQCEAFNPV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	29/135 (21%)
		ig	102..195	CDD:278476	24/111 (22%)
		IG_like	219..307	CDD:214653	20/93 (22%)
		Ig	221..307	CDD:299845	20/91 (22%)
		Ig	311..404	CDD:299845	21/88 (24%)
		IG_like	327..405	CDD:214653	16/69 (23%)
Psg18	NP_036093.2	Ig_CEACAM_D1	36..141	CDD:143251	3/15 (20%)
		IG_like	<104..138	CDD:214653	3/12 (25%)
		Ig_CEACAM_D1	157..261	CDD:143251	35/166 (21%)
		Ig_CEACAM_D1	277..379	CDD:143251	27/131 (21%)
		IG_like	396..473	CDD:214653	17/75 (23%)
		IGc2	401..462	CDD:197706	16/70 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000