DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-beta and Lrit1

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_647547.2 Gene:Lrit1 / 246214 RGDID:628607 Length:623 Species:Rattus norvegicus


Alignment Length:395 Identity:79/395 - (20%)
Similarity:138/395 - (34%) Gaps:122/395 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   211 PDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGS-HQKTKAQSVEGEML 274
            |::....||  ::.|.|.:..|.|.|.|.|.|:::|||.:||.:   ||: ||:..:......:|
  Rat   254 PELRPGVTS--IISPLGSTVLLRCGATGIPGPEMSWRRANGRPL---NGTVHQEVSSDGSSWTLL 313

  Fly   275 TLSKITRSEMGAYMCIASN-----------------------GVPPTVSKRM-----------KL 305
            .|..::..:.|.|:|.|.|                       |:|..:..|.           ||
  Rat   314 DLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTEYTGIPGALWARTGEGAEAAAYNNKL 378

  Fly   306 QVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAI 370
            .....|.|..|..|...|.:..:.     |..|       .:|.:|.:.|:   .:.:.:.....
  Rat   379 VARHVPHVPEPVALATKPSVPSIK-----EELP-------LQNFQMDVPGE---FSREPSEHQET 428

  Fly   371 EMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERPGKKILRDDDLNEVSKNEVV-----Q 430
            :|:..:|                .:|||..::.|         :.:.......:...|:     |
  Rat   429 QMVRSLK----------------VVGDTYHSVSL---------VWKAPQAGNTTAFSVLYAVFGQ 468

  Fly   431 KDTRS---EDG--SRNLNGRLYKDR------------APDQHPASGSDQLL-GRGTMRLIGTFLL 477
            :|.|.   |.|  |..:.|...|.:            ..:|.....:|::: ..||.|||...::
  Rat   469 RDMRRMTVEAGKTSVTIEGLAPKTKYVACVCVRGLVPTKEQCVIFSTDEVVDAEGTQRLINMVVI 533

  Fly   478 ALLVLFTALAEAGPTTLSC---------RTKGGRQKKAKETSWNGRRARDGREDGHAAEWRQCWE 533
            ::    .|:....||.|.|         :.:.|...:|.....|..|.      ||:.:..:...
  Rat   534 SV----AAIIALPPTLLVCCGALRRRCHKCRAGGSAEASGAYVNLERL------GHSEDGSEELS 588

  Fly   534 RSALS 538
            ||:||
  Rat   589 RSSLS 593

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352
ig 102..195 CDD:278476
IG_like 219..307 CDD:214653 30/122 (25%)
Ig 221..307 CDD:299845 29/120 (24%)
Ig 311..404 CDD:299845 15/92 (16%)
IG_like 327..405 CDD:214653 10/77 (13%)
Lrit1NP_647547.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..128
LRR_8 131..>176 CDD:290566
LRR_4 131..172 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 257..345 CDD:299845 26/92 (28%)
IG_like 267..345 CDD:214653 23/80 (29%)
FN3 431..501 CDD:214495 14/94 (15%)
LRR 6 525..548 7/26 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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