DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-beta and Lrit3

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001274153.1 Gene:Lrit3 / 242235 MGIID:2685267 Length:681 Species:Mus musculus


Alignment Length:284 Identity:55/284 - (19%)
Similarity:101/284 - (35%) Gaps:90/284 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 CIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKA 145
            |:||: ||:::::   .|||:....::.:...|...|                  .|.::     
Mouse   157 CLDLS-SNRLTTL---PPDFLDSWSHLAVTPSRSPDF------------------PPRRI----- 194

  Fly   146 DAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYM--CQVNTDPMKM-------- 200
                ||.:.:                |.|..:....|:.:..|..  ..|..||:.:        
Mouse   195 ----ILGLQD----------------NPWFCDCHISKVIELSKVTDHAVVLLDPLMVCSEPERFQ 239

  Fly   201 ----QTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSH 261
                |...||..:.|.::...|.  :....|.:..|.|.|:|||.|::||.|.||..:  .....
Mouse   240 GILFQRVELEKCLKPSVMMSATK--ITSALGSNVLLRCDAKGHPTPQLTWTRSDGSTV--NYTVI 300

  Fly   262 QKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLT 326
            |::..:.:...:::|:.|:..:.|.|.|.|.|                  |..:...:|...|:.
Mouse   301 QESPGEGIRWSIISLTSISHKDAGDYRCKAKN------------------LAGISEAVVTVTVVG 347

  Fly   327 DVTLICNVEASPKAINYWQRENGE 350
            .||...:.::|       :|..||
Mouse   348 GVTTTLSPDSS-------ERSPGE 364

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352 18/124 (15%)
ig 102..195 CDD:278476 10/94 (11%)
IG_like 219..307 CDD:214653 21/87 (24%)
Ig 221..307 CDD:299845 21/85 (25%)
Ig 311..404 CDD:299845 9/40 (23%)
IG_like 327..405 CDD:214653 6/24 (25%)
Lrit3NP_001274153.1 LRR 1. /evidence=ECO:0000255 56..79
LRR_8 61..117 CDD:290566
LRR 2. /evidence=ECO:0000255 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3. /evidence=ECO:0000255 104..128
LRR_8 105..165 CDD:290566 5/8 (63%)
LRR_4 106..146 CDD:289563
leucine-rich repeat 107..130 CDD:275378
LRR_4 129..170 CDD:289563 5/16 (31%)
LRR 4. /evidence=ECO:0000255 129..151
leucine-rich repeat 131..154 CDD:275378
LRR 5. /evidence=ECO:0000255 152..175 8/21 (38%)
leucine-rich repeat 155..168 CDD:275378 5/11 (45%)
Ig 254..335 CDD:299845 24/102 (24%)
IG_like 263..339 CDD:214653 22/95 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..391 5/22 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..464
FN3 489..563 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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