DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-beta and Lrit1

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_666357.2 Gene:Lrit1 / 239037 MGIID:2385320 Length:624 Species:Mus musculus


Alignment Length:382 Identity:76/382 - (19%)
Similarity:138/382 - (36%) Gaps:96/382 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   211 PDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGS-HQKTKAQSVEGEML 274
            |::....||  ::.|.|.:..|.|.|.|.|.|:::|||.:||.:   ||: ||:..:......:|
Mouse   255 PELRPGVTS--IISPLGSTVLLRCGATGIPGPEMSWRRANGRPL---NGTVHQEVSSDGSSWTLL 314

  Fly   275 TLSKITRSEMGAYMCIASN-----------------------GVPPTVSKRMKLQVHFHPLVQVP 316
            .|..::..:.|.|:|.|.|                       |:|..:..|......   .....
Mouse   315 DLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTGYSGIPGVLWARTGEGAE---AAAYN 376

  Fly   317 NQLVG--APVLTDVTLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRL 379
            |:||.  .|.:.:...:....:.|........:|.:|.:.|:   .:.:.:.....:|:..:|.:
Mouse   377 NKLVARHVPHMPEHVALATKPSMPSIKEELALQNFQMDVPGE---FSREPSEHQEAQMVRSLKVV 438

  Fly   380 QSSDFGGYKCIS----KNSIGDTEGTIRLY------EMER----PGKKILRDDDLNEVSKNEVVQ 430
            ..:    |..:|    ....|:|.....||      :|.|    |||..:..:.|...:|     
Mouse   439 GDT----YHSVSLVWKAPQAGNTTAFSVLYAVFGHRDMRRMTVEPGKTSVTIEGLAPKTK----- 494

  Fly   431 KDTRSEDGSRNLNGRLY------KDRAP--DQHPASGSDQLL-GRGTMRLIGTFLLALLVLFTAL 486
                            |      :...|  :|.....:|::: ..||.|||...::::    .|:
Mouse   495 ----------------YVACVCVRGLVPTKEQCVIFSTDEVVDAEGTQRLINMVVISV----AAI 539

  Fly   487 AEAGPTTLSCRTKGGRQKKAKETSWNGRRARDG-----REDGHAAEWRQCWERSALS 538
            ....||.|.|  .|..:::..:....|.....|     ...||:.:..:...||:||
Mouse   540 IALPPTLLVC--CGALRRRCHKCRTGGSAEASGAYVNLERLGHSEDSSEVLSRSSLS 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352
ig 102..195 CDD:278476
IG_like 219..307 CDD:214653 28/111 (25%)
Ig 221..307 CDD:299845 27/109 (25%)
Ig 311..404 CDD:299845 14/98 (14%)
IG_like 327..405 CDD:214653 10/81 (12%)
Lrit1NP_666357.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..>176 CDD:290566
LRR_4 131..172 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>241 CDD:301599
Ig 258..346 CDD:299845 26/92 (28%)
IG_like 268..346 CDD:214653 23/80 (29%)
FN3 432..502 CDD:214495 15/94 (16%)
LRR 6 526..549 7/26 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.