DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Ptprq

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001357916.1	Gene:	Ptprq / 237523	MGIID:	1096349	Length:	2301	Species:	Mus musculus

Alignment Length:	307	Identity:	63/307 - (20%)
Similarity:	96/307 - (31%)	Gaps:	114/307 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LLLLLLLGNCI--DLTVSNKISSVGAFEP------DFVIPLEN-VTIA--QGRDATFTCVVNNLG 125
            :|.::|||..|  ...:..|....|.:.|      |....|:. :|:|  :.:|...|    .|.
Mouse  1916 ILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLT----RLL 1976

  Fly   126 GHRVSGDGSSAPAKVAWIKADAKAILAIH-EHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKY 189
            .:|.|            ||..:|.....| |.:.|||:
Mouse  1977 SYRKS------------IKPVSKKSFLQHVEELCTNNN--------------------------- 2002

  Fly   190 MCQVNTDPMKMQTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGR-- 252
                    :|.|....|:   |..:.:.:|.|..:|                    |.|...|
Mouse  2003 --------LKFQEEFSEL---PKFLQDLSSTDADLP--------------------WNRAKNRFP 2036

  Fly   253 EIIARNGSHQKTKAQ-SVEGEMLTLSKITRSEMGAYMC----IASNG-VPPTVSK--RMKLQVHF 309
            .|...|.:..|..|. |:.|.    ..|..|.:..|:|    ||:.| :|.||..  ||..:...
Mouse  2037 NIKPYNNNRVKLIADVSIPGS----DYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRA 2097

  Fly   310 HPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGD 356
            ..||          :||.    |..:...:...||..:|..:.:.||
Mouse  2098 KTLV----------MLTQ----CFEKGRIRCHQYWPEDNKPVTVFGD 2130

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	21/120 (18%)
		ig	102..195	CDD:278476	16/96 (17%)
		IG_like	219..307	CDD:214653	24/97 (25%)
		Ig	221..307	CDD:299845	23/95 (24%)
		Ig	311..404	CDD:299845	10/46 (22%)
		IG_like	327..405	CDD:214653	6/30 (20%)
Ptprq	NP_001357916.1	FN3	57..151	CDD:238020
		FN3	308..393	CDD:238020
		fn3	399..>441	CDD:365830
		FN3	570..654	CDD:238020
		fn3	668..744	CDD:365830
		FN3	762..850	CDD:238020
		fn3	857..934	CDD:365830
		FN3	951..1049	CDD:238020
		FN3	1056..1137	CDD:238020
		FN3	1152..1233	CDD:238020
		FN3	1247..1337	CDD:238020
		FN3	1342..1421	CDD:238020
		FN3	1432..1535	CDD:238020
		FN3	1542..1638	CDD:238020
		FN3	1645..1734	CDD:238020
		UP_III_II	1759..1928	CDD:297589	5/11 (45%)
		R-PTPc-Q	2033..2256	CDD:350464	29/116 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900