DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Tapbpl

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_663366.2	Gene:	Tapbpl / 213233	MGIID:	2384853	Length:	451	Species:	Mus musculus

Alignment Length:	427	Identity:	91/427 - (21%)
Similarity:	146/427 - (34%)	Gaps:	141/427 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LVVKESGERIADISCSQEHTT----KFSPKLSQVAKHRK----LAQLEIASGSGLVGLGTGTGTG 61
            ||.....|.:....||.:..|    |:..:..|.|...|    ::.::::.|
Mouse   105 LVQIPQAEALLHADCSGKAVTCEISKYFLQARQEATFEKAHWFISNMQVSRG------------- 156

  Fly    62 SGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAF-EPDFVIPLENVTIAQGRDAT--------F 117
               ||::...:..|             :.:.|||. .|...:||.    |||...|        .
Mouse   157 ---GPSVSMVMKTL-------------RDAEVGAVRHPTLNLPLS----AQGTVKTQVEFQVTSE 201

  Fly   118 TCVVNNLGGHRVS--GDGSSAP----AKVAWI----------------KADAK---AILAIHEHV 157
            |..:|:|.|..||  ...|.||    ..|.|.                :..||   |.|...|.:
Mouse   202 TQTLNHLLGSSVSLHCSFSMAPGLDLTGVEWRLQHKGSGQLVYSWKTGQGQAKRKGATLEPEELL 266

  Fly   158 ITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMK-MQTATLEVVIPPDIINEETSGD 221
            ...|.            :|.:..:.::|.|.|:||::|...: .|...|.::.||.|.....:.|
Mouse   267 RAGNA------------SLTLPNLTLKDEGNYICQISTSLYQAQQIMPLNILAPPKIQLHLANKD 319

  Fly   222 MMVPEGGSAKLVCRARG-HP-KPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEM 284
            .:      ..|||...| :| ...:||.||:...|.|:           |.|  .:.|.:.:|.|
Mouse   320 PL------PSLVCSIAGYYPLDVGVTWIREELGGIPAQ-----------VSG--ASFSSLRQSTM 365

  Fly   285 GAY----MCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQ 345
            |.|    ..:|..|  ||.:..         ..||.:..:..|:.|.:.::.|.|         |
Mouse   366 GTYSISSTVMADPG--PTGATY---------TCQVAHVSLEEPLTTSMRVLPNPE---------Q 410

  Fly   346 RENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSS 382
            |....:|.|...:        :.|:.:.|.:.|.|:|
Mouse   411 RGTLGVIFASIIF--------LSALLLFLGLHRQQAS 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	33/144 (23%)
		ig	102..195	CDD:278476	29/125 (23%)
		IG_like	219..307	CDD:214653	23/93 (25%)
		Ig	221..307	CDD:299845	23/91 (25%)
		Ig	311..404	CDD:299845	15/72 (21%)
		IG_like	327..405	CDD:214653	11/56 (20%)
Tapbpl	NP_663366.2	V-set	209..306	CDD:284989	23/108 (21%)
		IG_like	209..299	CDD:214653	21/101 (21%)
		Ig	271..401	CDD:299845	38/171 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000