DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Skint3

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001095944.1	Gene:	Skint3 / 195564	MGIID:	3045331	Length:	458	Species:	Mus musculus

Alignment Length:	214	Identity:	46/214 - (21%)
Similarity:	90/214 - (42%)	Gaps:	49/214 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 MMVPEGGSAKLVCR---ARGHPKPKITWRREDGRE--IIARNGS--HQKTKAQSVE--------- 270
            ::.|.||..:|.|:   .:...:.:|.|.|....|  .:.|||.  |.:|.::.||
Mouse    37 VLAPLGGILELSCQLSPPQNAQQMEIRWFRNRYTEPVYLYRNGKDLHGETISKYVERTELLKHDI 101

  Fly   271 --GEM-LTLSKITRSEMGAYMCIASNGV--------PPTVSKRMKLQVHFHPLVQVPNQLVGAPV 324
              |:: |.:.|:|..:.|:|.|:..:|:        ....:....:::..||           |.
Mouse   102 GKGKVTLRVFKVTVDDDGSYHCVFKDGIFYEEHITEVKVTATSSDIKIIMHP-----------PN 155

  Fly   325 LTDVTLICNVEA-SPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYK 388
            :..|.|.|:... .|:....|:..||::|.|..: :.::.||.::.:.|.|.      :|.|.::
Mouse   156 IKGVMLECHSRGWFPQPHMEWRDSNGQVIPATSK-SQSQDENKLFNMTMNLF------ADVGLHQ 213

  Fly   389 ---CISKNSIGDTEGTIRL 404
               |..:|.:...|.:|.:
Mouse   214 IVTCYIQNLLTHQEESISI 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352
		ig	102..195	CDD:278476
		IG_like	219..307	CDD:214653	24/111 (22%)
		Ig	221..307	CDD:299845	24/111 (22%)
		Ig	311..404	CDD:299845	21/96 (22%)
		IG_like	327..405	CDD:214653	19/82 (23%)
Skint3	NP_001095944.1	IG_like	35..140	CDD:214653	24/102 (24%)
		Ig_MOG_like	42..141	CDD:143190	23/98 (23%)
		Ig	159..221	CDD:299845	16/68 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000