DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-beta and Ncam2

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001106679.1 Gene:Ncam2 / 17968 MGIID:97282 Length:837 Species:Mus musculus


Alignment Length:328 Identity:87/328 - (26%)
Similarity:136/328 - (41%) Gaps:83/328 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 PDFVIPLE--NVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITN 160
            |..::|.:  |.|..:|.:.|.||          ...||..|. ::|.:                
Mouse   209 PAIMMPQKSFNATAERGEEMTLTC----------KASGSPDPT-ISWFR---------------- 246

  Fly   161 NDRLSVQHNDY-----NTWTLNIRGVKMEDAGKYMCQ-VNTDPMKMQTATLEVVIPPDII---NE 216
            |.:|..::..|     || .|.:|.:..:|.|.|:|: .|......:.|.|:|.:.|.|:   ||
Mouse   247 NGKLIEENEKYILKGSNT-ELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNE 310

  Fly   217 ETSGDMMVPEGGSAKLVCRARGHPKPKITWRR-------------EDGREIIARNGSHQKTKAQS 268
            .||      |.|...|||.|.|.|.|:|||:|             .|||  |...|.|.::.   
Mouse   311 TTS------ENGHVTLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGR--IEVKGQHGRSS--- 364

  Fly   269 VEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLV-----GAPVLTDV 328
                 |.:..:..|:.|.|.|.|::.:... .:.|.|.:.:.|.. |.||.:     |.|    :
Mouse   365 -----LHIRDVKLSDSGRYDCEAASRIGGH-QRSMHLDIEYAPKF-VSNQTMYYSWEGNP----I 418

  Fly   329 TLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKN 393
            .:.|:|.|:|.|..:|:||  ::::....  .|..:.:....:|||.|.....:|||.|.|.:.|
Mouse   419 NISCDVTANPPASIHWRRE--KLLLPAKN--TTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATN 479

  Fly   394 SIG 396
            .||
Mouse   480 RIG 482

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352 27/118 (23%)
ig 102..195 CDD:278476 22/100 (22%)
IG_like 219..307 CDD:214653 28/100 (28%)
Ig 221..307 CDD:299845 27/98 (28%)
Ig 311..404 CDD:299845 27/91 (30%)
IG_like 327..405 CDD:214653 21/70 (30%)
Ncam2NP_001106679.1 Ig1_NCAM-2 21..112 CDD:143274
I-set 22..111 CDD:254352
I-set 117..193 CDD:254352
IGc2 128..189 CDD:197706
Ig 208..301 CDD:299845 27/119 (23%)
I-set 215..298 CDD:254352 24/110 (22%)
Ig 300..397 CDD:299845 33/113 (29%)
IG_like 308..395 CDD:214653 30/103 (29%)
IG_like 413..491 CDD:214653 23/78 (29%)
IGc2 414..482 CDD:197706 21/75 (28%)
FN3 496..588 CDD:238020
fn3 594..678 CDD:278470
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 764..810
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

Return to query results.
Submit another query.