Protein Alignment DIP-beta and Ncam2

DIOPT Version :10

• Sequence 1: NP_001138225.1
• Gene: DIP-beta / 33125
• FlyBaseID: FBgn0259245
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001106679.1
• Gene: Ncam2 / 17968
• MGIID: 97282
• Length: 837
• Species: Mus musculus
• Alignment Length: 328
• Identity: 87/328 - (26%)
• Similarity: 136/328 - (41%)
• Gaps: 83/328 - (25%)

  Fly    98 PDFVIPLE--NVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITN 160
            |..::|.:  |.|..:|.:.|.||          ...||..|. ::|.:
Mouse   209 PAIMMPQKSFNATAERGEEMTLTC----------KASGSPDPT-ISWFR---------------- 246

  Fly   161 NDRLSVQHNDY-----NTWTLNIRGVKMEDAGKYMCQ-VNTDPMKMQTATLEVVIPPDII---NE 216
            |.:|..::..|     || .|.:|.:..:|.|.|:|: .|......:.|.|:|.:.|.|:   ||
Mouse   247 NGKLIEENEKYILKGSNT-ELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNE 310

  Fly   217 ETSGDMMVPEGGSAKLVCRARGHPKPKITWRR-------------EDGREIIARNGSHQKTKAQS 268
            .||      |.|...|||.|.|.|.|:|||:|             .|||  |...|.|.::.
Mouse   311 TTS------ENGHVTLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGR--IEVKGQHGRSS--- 364

  Fly   269 VEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLV-----GAPVLTDV 328
                 |.:..:..|:.|.|.|.|::.:... .:.|.|.:.:.|.. |.||.:     |.|    :
Mouse   365 -----LHIRDVKLSDSGRYDCEAASRIGGH-QRSMHLDIEYAPKF-VSNQTMYYSWEGNP----I 418

  Fly   329 TLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKN 393
            .:.|:|.|:|.|..:|:||  ::::....  .|..:.:....:|||.|.....:|||.|.|.:.|
Mouse   419 NISCDVTANPPASIHWRRE--KLLLPAKN--TTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATN 479

  Fly   394 SIG 396
            .||
Mouse   480 RIG 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	Ig	98..209	CDD:472250	27/118 (23%)
		Ig strand B	115..119	CDD:409353	1/3 (33%)
		Ig strand C	139..143	CDD:409353	0/3 (0%)
		Ig strand E	174..178	CDD:409353	1/3 (33%)
		Ig strand F	188..193	CDD:409353	2/5 (40%)
		Ig strand G	202..205	CDD:409353	1/2 (50%)
		Ig	211..307	CDD:472250	33/111 (30%)
		Ig strand B	230..234	CDD:409353	1/3 (33%)
		Ig strand C	243..247	CDD:409353	2/3 (67%)
		Ig strand E	272..276	CDD:409353	1/3 (33%)
		Ig strand F	286..291	CDD:409353	2/4 (50%)
		Ig strand G	300..303	CDD:409353	0/2 (0%)
		IG_like	327..405	CDD:214653	21/70 (30%)
		Ig strand B	328..332	CDD:409353	0/3 (0%)
		Ig strand C	341..346	CDD:409353	1/4 (25%)
		Ig strand E	365..376	CDD:409353	3/10 (30%)
		Ig strand F	386..391	CDD:409353	2/4 (50%)
		Ig strand G	399..402	CDD:409353
Ncam2	NP_001106679.1	IgI_1_NCAM-2	21..113	CDD:409452
		Ig strand A	21..26	CDD:409452
		Ig strand A'	29..33	CDD:409452
		Ig strand B	35..45	CDD:409452
		Ig strand C	49..55	CDD:409452
		Ig strand C'	58..60	CDD:409452
		Ig strand D	66..72	CDD:409452
		Ig strand E	74..82	CDD:409452
		Ig strand F	89..96	CDD:409452
		Ig strand G	101..112	CDD:409452
		IG_like	122..187	CDD:214653
		Ig strand B	132..136	CDD:409353
		Ig strand C	145..152	CDD:409353
		Ig strand E	169..173	CDD:409353
		Ig strand F	183..187	CDD:409353
		Ig strand G	191..194	CDD:409353
		IgI_1_MuSK	209..298	CDD:409562	26/116 (22%)
		Ig strand A	209..212	CDD:409562	1/2 (50%)
		Ig strand A'	217..222	CDD:409562	1/4 (25%)
		Ig strand B	228..235	CDD:409562	3/16 (19%)
		Ig strand C	241..246	CDD:409562	1/5 (20%)
		Ig strand C'	248..250	CDD:409562	0/1 (0%)
		Ig strand D	257..260	CDD:409562	1/2 (50%)
		Ig strand E	264..270	CDD:409562	2/6 (33%)
		Ig strand F	277..284	CDD:409562	3/6 (50%)
		Ig strand G	290..298	CDD:409562	2/7 (29%)
		Ig	300..397	CDD:472250	33/113 (29%)
		Ig strand B	318..322	CDD:409353	1/3 (33%)
		Ig strand C	331..335	CDD:409353	2/3 (67%)
		Ig strand E	363..367	CDD:409353	1/11 (9%)
		Ig strand F	377..382	CDD:409353	2/4 (50%)
		Ig strand G	390..393	CDD:409353	0/2 (0%)
		Ig_3	401..479	CDD:464046	24/86 (28%)
		FN3	496..588	CDD:238020
		fn3	594..678	CDD:394996
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	764..810