DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Psg29

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_473405.1	Gene:	Psg29 / 114872	MGIID:	1891361	Length:	468	Species:	Mus musculus

Alignment Length:	499	Identity:	99/499 - (19%)
Similarity:	150/499 - (30%)	Gaps:	207/499 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 GCGPAIRWQ-LLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGG 126
            ||.|   || :||......|..|:.::|::          |.|....:.:|.|..|  :||||.|
Mouse    11 GCAP---WQGVLLTASFLTCWYLSTTSKVT----------IELLPSQVVEGEDVLF--LVNNLPG 60

  Fly   127 ------------HRVSGDGSSAPAKVAWIKADAKAI-----LAIHEHVITNNDR----------- 163
                        :|..|....|.|...::.:|.:.:     |.||.  :|..||
Mouse    61 NLTAFAWFKGRTNRKHGIALYAVASDLYVHSDRETLYNNGSLMIHN--VTQKDRGYYTLRTFNKH 123

  Fly   164 ----------LSV----------------------------QH---NDYN--------TW----- 174
                      |.|                            ||   :.||        .|
Mouse   124 AETVSTTFTFLHVNPFLWNCGRLVTSSQPRIESFPSIVTEGQHVILHVYNIPENLQGFIWFKGMT 188

  Fly   175 ---------------------------------TLNIRGVKMEDAGKYMCQVNTDPMKMQTATLE 206
                                             :|.|..|..:|||.|..:|....||.:.|.:|
Mouse   189 VHRHLEIGRYTIGRKSSVFGPAYSGREKLDSNGSLRIENVTQKDAGLYTLRVLGTDMKSEEAHVE 253

  Fly   207 VVI--PP-DIINEETSGDMM-------VPEGGSAKLVCRARGHPKPK----ITWRRE-------- 249
            :.:  |. ...|..||..:|       |.||.|..|:.    |..|:    .||...
Mouse   254 LQVNNPAFQCCNPSTSSKLMVEAVPRYVAEGESVLLLV----HNLPEELISFTWYNSMYRVPAFK 314

  Fly   250 -----------------DGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPP 297
                             .||:.:..|||             |.|..:|..:...|.....| |..
Mouse   315 IVEFNVIRNITTWGDVYRGRDTVYANGS-------------LMLQDVTEEDARMYTLETLN-VNY 365

  Fly   298 TVSKRMKLQVHFH-----PLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGDR 357
            || :|..:|.:.:     |.||:.:....|.  ..:|..|.......:|.::  .|...:...:|
Mouse   366 TV-ERAHVQFYVNKPVTQPFVQITDTTANAQ--RSLTFTCVTPDIATSILWF--FNSHSLKPTER 425

  Fly   358 YALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGT 401
            ..|:..:..       |.|..::|.|.|.|:|:..|..||.:.:
Mouse   426 ITLSPTKCG-------LRIDDVRSEDAGNYQCVVVNRNGDAKAS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	40/225 (18%)
		ig	102..195	CDD:278476	36/207 (17%)
		IG_like	219..307	CDD:214653	25/123 (20%)
		Ig	221..307	CDD:299845	24/121 (20%)
		Ig	311..404	CDD:299845	20/91 (22%)
		IG_like	327..405	CDD:214653	16/75 (21%)
Psg29	NP_473405.1	Ig_CEACAM_D1	36..136	CDD:143251	22/113 (19%)
		Ig_CEACAM_D1	152..256	CDD:143251	17/103 (17%)
		IG_like	<209..256	CDD:214653	12/46 (26%)
		Ig_CEACAM_D1	272..376	CDD:143251	25/122 (20%)
		I-set	384..462	CDD:254352	19/88 (22%)
		IGc2	396..457	CDD:197706	14/69 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000