DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Psg28

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_473404.3	Gene:	Psg28 / 114871	MGIID:	1891360	Length:	472	Species:	Mus musculus

Alignment Length:	410	Identity:	84/410 - (20%)
Similarity:	144/410 - (35%)	Gaps:	134/410 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SGCGPAIRWQ-LLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLG 125
            :||   ..|| :||...|..|..|..:.:: ::.:|.|. |:..|||.:.          |:|:
Mouse    10 NGC---TSWQRVLLTAFLLTCWHLPTTARV-TIESFPPQ-VVEGENVLLR----------VDNM- 58

  Fly   126 GHRVSGDGSSAPAKV---AWIK--ADAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMED 185
                       |..:   .|.:  .:.:..:|::..:.....:.|.:...|...:|.|:.|..||
Mouse    59 -----------PENLLVFGWYRGMTNLRHAIALYYSLTAKGLKHSGRETLYINGSLWIQNVTQED 112

  Fly   186 AGKYMCQVNTDPMKM------------------QTATLEVVIPPDIINEETSGDMMVPEGGSAKL 232
            .|.|..|..:...:|                  ::.|||   .|.|....||    |..|||..|
Mouse   113 TGYYTFQTISKQGEMVSNTSLYLHVYSSLFICGRSTTLE---GPTIELVPTS----VAAGGSVLL 170

  Fly   233 VCRARGHPKPK----ITW---------------RR----------EDGREIIARNGSHQKTKAQS 268
            :.    |..||    :.|               ||          ..|||.:.||||
Mouse   171 LV----HNIPKYLQSLFWYKGLIVFNKVEIARYRRAKKSREPGPAHSGRETVYRNGS-------- 223

  Fly   269 VEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLIC- 332
                 |.|..:|..:.|.|..       .|:::..|::: .|..:||.         |.::|.|
Mouse   224 -----LLLKNVTWKDTGFYTL-------RTLTRYQKMEL-AHIYLQVD---------TSLSLCCD 266

  Fly   333 ---NVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFG-GYKCI--- 390
               :.:.|...:.....|.|.:::  ..|.|.|........:.:|..:..:.:::. ..|.|
Mouse   267 TLDSAQLSIDPVPQHAAEGGSVLL--QVYNLPEGLQTFSWYKGVLSTQDFKIAEYSIATKSIIRG 329

  Fly   391 ---SKNSIGDTEGTIRLYEM 407
               |:..||.|.|::.|.::
Mouse   330 RAHSRREIGYTNGSLLLQDV 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	24/133 (18%)
		ig	102..195	CDD:278476	18/97 (19%)
		IG_like	219..307	CDD:214653	26/116 (22%)
		Ig	221..307	CDD:299845	25/114 (22%)
		Ig	311..404	CDD:299845	19/103 (18%)
		IG_like	327..405	CDD:214653	16/88 (18%)
Psg28	NP_473404.3	Ig_CEACAM_D1	36..137	CDD:143251	22/124 (18%)
		IG_like	45..134	CDD:214653	20/110 (18%)
		Ig_CEACAM_D1	153..257	CDD:143251	30/132 (23%)
		Ig_CEACAM_D1	273..375	CDD:143251	15/79 (19%)
		IG_like	277..375	CDD:214653	14/75 (19%)
		IG_like	392..469	CDD:214653
		IGc2	397..458	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000