DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Psg25

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_473401.1	Gene:	Psg25 / 114868	MGIID:	1891357	Length:	475	Species:	Mus musculus

Alignment Length:	358	Identity:	77/358 - (21%)
Similarity:	131/358 - (36%)	Gaps:	93/358 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 LENVT--IAQGRDATFTCVVNNLGGH-----RVSGDGSSAPAKVAWIKADAKAILAIH---EH-- 156
            ||:.|  ..|...:||.|      ||     :::.:  |.|..||   |....:|.:|   ||
Mouse   130 LESNTSMFLQVYSSTFIC------GHPFFPAKLTIE--SVPPSVA---AGGSVLLRVHNLPEHLQ 183

  Fly   157 --------VITNNDRL----------------SVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDP 197
                    ::.|...:                |.:...|:..:|.::.|..:|.|.|..:.....
Mouse   184 SLFWYKGLIVFNKVEIARYRTAKNSSEPGHAHSGRETVYSNGSLLLQDVTWKDTGFYTLRTLNRY 248

  Fly   198 MKMQTA--TLEVVIPPDIINEETSGDMM----VP----EGGSAKLVCRARGHPKPK----ITW-- 246
            .||:.|  .|:|..|..:..:......:    ||    ||||..|    :.|..|:    .:|
Mouse   249 RKMKLAHIYLQVDTPLSLCCDTLDFAQLSIDPVPRYAVEGGSVLL----QVHNLPEDLQTFSWYK 309

  Fly   247 --RREDGREI---------IARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVS 300
              ....|.:|         |....:|.:.:....:|.:| |..:|..:.|.|..||.:.....|.
Mouse   310 GVHNTHGFKIAEYSIATKSIISGRAHSRREIGYTDGSLL-LQDVTEKDSGLYTLIAIDSNVRVVR 373

  Fly   301 KRMKLQVH---FHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGDRYALTE 362
            ..:::.||   ..|:|:|.:..|  .|.:.|...|..:.:..:|. |...|..:       .|||
Mouse   374 AHVQVNVHKLVTQPVVRVTDTTV--RVQSSVVFTCFSDNTRISIR-WLFNNQNL-------QLTE 428

  Fly   363 KENNMYAIEMILHIKRLQSSDFGGYKCISKNSI 395
            : ..:...:..|.|..::..|.|.|:|.:.|.:
Mouse   429 R-MTLSPSKCQLRIHTVRKEDAGEYQCEAFNPV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	31/142 (22%)
		ig	102..195	CDD:278476	26/126 (21%)
		IG_like	219..307	CDD:214653	23/112 (21%)
		Ig	221..307	CDD:299845	23/110 (21%)
		Ig	311..404	CDD:299845	20/85 (24%)
		IG_like	327..405	CDD:214653	15/69 (22%)
Psg25	NP_473401.1	Ig_CEACAM_D1	36..140	CDD:143251	3/9 (33%)
		IG_like	42..140	CDD:214653	3/9 (33%)
		Ig_CEACAM_D1	156..260	CDD:143251	21/108 (19%)
		Ig_CEACAM_D1	276..380	CDD:143251	23/108 (21%)
		IG_like	280..380	CDD:214653	23/104 (22%)
		IG_like	393..472	CDD:214653	17/79 (22%)
		IGc2	400..461	CDD:197706	15/70 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000