DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and ntm

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	97/316 - (30%)
Similarity:	149/316 - (47%)	Gaps:	56/316 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 LENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQ- 167
            ::|||:.||..|...|.|:|    ||:        :|||:  :...||      .|.||:.|:.
Frog    43 MDNVTVRQGDSAILRCTVDN----RVT--------RVAWL--NRSTIL------YTGNDKWSIDP 87

  Fly   168 -----HNDYNTWTLNIRGVKMEDAGKYMCQVNTD--PMKMQTATLEVVIPPDIINEETSGDMMVP 225
                 .|..:.:::.|:.|.:.|.|.|.|.|.||  | |.....|.|.:||.|:  :.|..:.|.
Frog    88 RVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHP-KTSRVHLIVQVPPRIV--DISSSIAVN 149

  Fly   226 EGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSV--EGEMLTLSKITRSEMGAYM 288
            ||.:..|:|.|.|.|:|.:.||             :...||:..  |.|.|.::.|||.:.|.|.
Frog   150 EGSNVSLICIANGRPEPVVNWR-------------YLSPKARGFVSEDEYLEITGITREQSGIYE 201

  Fly   289 CIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMII 353
            |.|||.|.....:|:||.|::.|.: :..|.:|||:.....|.|...|.|.|..:|.:|:..:
Frog   202 CSASNDVSAPDVRRVKLTVNYPPYI-LDAQNIGAPLGHRGILQCEASAVPAADFFWYKEDKRL-- 263

  Fly   354 AGDRYALTEKENNMYAIEMILHIKRLQSS--DFGGYKCISKNSIGDTEGTIRLYEM 407
             .|.:...:.||.    |.|..:..|..|  |:|.|.|::||.:|.:..:|.|:|:
Frog   264 -SDSWRGVKVENR----ETISRVTFLNVSEQDYGNYTCMAKNLLGHSNASIILFEL 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	34/112 (30%)
		ig	102..195	CDD:278476	28/96 (29%)
		IG_like	219..307	CDD:214653	30/89 (34%)
		Ig	221..307	CDD:299845	29/87 (33%)
		Ig	311..404	CDD:299845	27/94 (29%)
		IG_like	327..405	CDD:214653	22/79 (28%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	33/108 (31%)
		IG_like	45..133	CDD:214653	33/108 (31%)
		IG_like	143..220	CDD:214653	30/89 (34%)
		IGc2	150..209	CDD:197706	24/71 (34%)
		ig	227..311	CDD:278476	26/90 (29%)
		IG_like	230..311	CDD:214653	26/87 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm47726
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060