DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and iglon5

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	91/327 - (27%)
Similarity:	160/327 - (48%)	Gaps:	49/327 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 DFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDR 163
            :||.|.:|.|::||.:||.:|::::    :|:        :|||:  :...||...:...:.:.|
Frog    28 EFVPPADNYTVSQGDNATLSCLIDD----KVT--------RVAWL--NRSNILYAGKDKWSIDSR 78

  Fly   164 LSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTAT--LEVVIPPDIINEETSGDMMVPE 226
            :.:..|..:.:::.|..|.:.|.|.|.|...|:. |..|:.  |.|.:|..|:|  .|..:.|.|
Frog    79 VQLLTNTKSEYSIVITHVDVADEGLYTCSFQTED-KPHTSQVYLIVQVPAKIVN--ISSSVTVNE 140

  Fly   227 GGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIA 291
            |.:..|.|.|.|.|:|.|||:              |.::..|.|||:|.:::|.|.:.|.|.|:.
Frog   141 GSNVNLQCLAVGKPEPTITWQ--------------QLSEGFSSEGELLEITEINRQQAGDYECVT 191

  Fly   292 SNGVPPTVSKRMKLQVHFHP-LVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAG 355
            ||||....:|::::.|::.| :..|.|  ..:||....||.|...|.|.|...|.::....:|:|
Frog   192 SNGVSVPDTKKVQITVNYPPYITDVKN--AQSPVGRPATLRCKAMAVPPAEFEWYKDEKRRLISG 254

  Fly   356 DRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERPGKKILRDDDL 420
            .. .|:.|..:.::   ::....:.|..:|.|.|::.|.:|....::||.   :||      |.|
Frog   255 TE-GLSIKTESSWS---VIVFSNVTSRHYGNYTCLASNKLGSFNSSLRLL---KPG------DPL 306

  Fly   421 NE 422
            |:
Frog   307 NQ 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	29/111 (26%)
		ig	102..195	CDD:278476	22/92 (24%)
		IG_like	219..307	CDD:214653	29/87 (33%)
		Ig	221..307	CDD:299845	28/85 (33%)
		Ig	311..404	CDD:299845	22/93 (24%)
		IG_like	327..405	CDD:214653	18/77 (23%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	26/106 (25%)
		IG_like	35..123	CDD:214653	25/102 (25%)
		Ig	126..207	CDD:299845	32/96 (33%)
		I-set	128..207	CDD:254352	31/94 (33%)
		I-set	210..299	CDD:254352	22/94 (23%)
		Ig	227..298	CDD:143165	17/74 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970