DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-beta and adgrl1.1

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_002660669.2	Gene:	adgrl1.1 / 100334775	ZFINID:	ZDB-GENE-130116-2	Length:	390	Species:	Danio rerio

Alignment Length:	283	Identity:	64/283 - (22%)
Similarity:	102/283 - (36%)	Gaps:	77/283 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 LTLSKITRSEMGAYMCIASNGV---PPTVSKRMKLQVHFHPLV------------QVPNQLVGAP 323
            |..:.:|.|.:...:|....||   |.|.:.|:...|.|...|            ::.||.:|..
Zfish     4 LQTAALTFSALLCAVCAQGPGVSVRPRTAAVRLGETVSFQHRVTSRAQPGMLESGKMNNQTLGVF 68

  Fly   324 VLTDVTLICNVEASPKAINYWQRENG----EMIIAGDR-YALTEKENNMYAIEMILHIKR----L 379
            |... ||:..:|  |.::...:..:|    :.:.|||| |.:..   ..|..:|:.....    :
Zfish    69 VCPG-TLVRVLE--PSSVREAEDHSGAWCKDPLQAGDRLYVMPW---TPYRTDMLYEYASWDDYI 127

  Fly   380 QSSDFGGYKCISKNSIGDT-----EGTIRLYEMERPGKKILRDDDLNEVSKNEVVQKDTRSEDGS 439
            |:.....||..|:  :..|     :|.: .|..||. :.|::.|....:...|.|..:....|.|
Zfish   128 QNRVTTTYKLPSR--VDGTGFVVYDGAV-FYNKERT-RNIVKYDLRTRIKSGEAVIVNANYHDAS 188

  Fly   440 -RNLNGRLYKDRAPDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAG--------PTTLS 495
             .:..|:...|.|.|:|                      .|.|::|..|..|        |.||
Zfish   189 PYHRGGKSDIDLAVDEH----------------------GLWVIYTTEANNGRLVVSQVNPYTL- 230

  Fly   496 CRTKGGRQKKAKETSWNGRRARD 518
             |.:|..|     ||:..|.|.|
Zfish   231 -RFEGTWQ-----TSFEKRMASD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352
		ig	102..195	CDD:278476
		IG_like	219..307	CDD:214653	9/35 (26%)
		Ig	221..307	CDD:299845	9/35 (26%)
		Ig	311..404	CDD:299845	23/118 (19%)
		IG_like	327..405	CDD:214653	18/91 (20%)
adgrl1.1	XP_002660669.2	OLF	72..328	CDD:295358	48/215 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010