Protein Alignment mst and DML1

DIOPT Version :9

• Sequence 1: NP_001285518.1
• Gene: mst / 33119
• FlyBaseID: FBgn0020272
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_013938.1
• Gene: DML1 / 855251
• SGDID: S000004824
• Length: 475
• Species: Saccharomyces cerevisiae
• Alignment Length: 480
• Identity: 110/480 - (22%)
• Similarity: 182/480 - (37%)
• Gaps: 118/480 - (24%)

  Fly     6 EILTFQFGTYANYVGTHFWNQQEANFRYGDESEQVAEEQLPNNDILYREGRNDLNRT-TYTPRLL 69
            |::|......||::.|.|:|.||...:...| :||.:.::..|.::     :.:::| :|.||.|
Yeast     3 EVVTISVSQRANHLTTQFFNIQEGYLQLSKE-QQVNDSKIFLNSVV-----DKVSKTISYAPRAL 61

  Fly    70 SVDL---SGTLGHLPVTGELYGNFVQRDEELLPLSTGEELEQVRKRAEESGVCSPEQLEVQEQSK 131
            ..|.   :|:||....:.....:|...|:                        ..||..::...:
Yeast    62 LWDARTGNGSLGTYQYSESQDYHFGNEDK------------------------FKEQTVIKTHPR 102

  Fly   132 ASISEYQRDLLKNAVVPEKNYQLAATANSWVDFLYARYHPRTLNVLPGLIRD------PTAQALG 190
            ...||||..|...|.:|..|.:   ....|.|:....|.|.:.|:|.....|      |..|.||
Yeast   103 IPKSEYQSSLDAGAPLPCLNRE---NTMYWSDYSKLIYGPSSFNILRNWYHDTENPNQPDFQNLG 164

  Fly   191 -----TYSAGTEMWQEVSFNEEFCDRIRLYVEECDGLQGFHVLFDIDDGFGGLAGKCLEHLNDEY 250
                 .||.|.:.:.|....|.|...:...:|:||.||||:::.|::.|:||.:...|..|.:|.
Yeast   165 ERKFDRYSIGYDEFTENYLQEFFDGNLHRELEKCDTLQGFNLVSDMESGWGGFSSALLVELRNEL 229

  Fly   251 SRASFALPLHY---PRITSYPQADTRLSHS-IRVVNNVL--GYHQLSEQALMFTPLSTLETIWRN 309
            .:.:.....|.   |....:|.  .|||.. :.:::|.|  ..:.:.|..|.| ||
Yeast   230 PKKAVFSWGHNEDDPFTDDFPM--KRLSKKWLPIISNKLRSTINMMQESDLYF-PL--------- 282

  Fly   310 NNLKSRSLPGL-QWET-----------------DNLYQTSALLAAFFDTA-TLSYRLRQTPESLL 355
                 .:.||| .|||                 .||.|...:  .:..|| ||.|..|.....::
Yeast   283 -----YAAPGLTNWETAGKSCRIFDSINATISQSNLEQRKTM--DYLTTAITLGYSSRNMVTGMV 340

  Fly   356 ------RFCECVTP--AGRKMTAAGLALPFGLREGQDLIEFLDQSGDHALLTQLTPGCEPGT-SY 411
                  .||..|.|  ...|..:..:.       .:..|:..:|:..|        ..||.: |.
Yeast   341 IGDTDYSFCSRVLPFKNSHKPNSTHIF-------SKSFIDRGNQTHKH--------HSEPDSRSK 390

  Fly   412 VVQSVTARGIPAERLKRPRELAGDQ 436
            :::..|.|..|::.:  |.|.:.|:
Yeast   391 MIEMYTHRYFPSDTI--PTEFSNDR 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mst	NP_001285518.1	misato	5..570	CDD:276964	110/480 (23%)
DML1	NP_013938.1	Tubulin_FtsZ_Cetz-like	2..>290	CDD:415827	81/336 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345767
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6100
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005869
OrthoInspector	1	1.000	-	-		oto100185
orthoMCL	1	0.900	-	-		OOG6_103867
Panther	1	1.100	-	-	LDO	PTHR13391
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2091
SonicParanoid	1	1.000	-	-		X4263
TreeFam	0	0.000	Not matched by this tool.
	11	10.720