DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hlc and AT2G40700

DIOPT Version :9

Sequence 1:	NP_001285517.1	Gene:	Hlc / 33118	FlyBaseID:	FBgn0001565	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_181602.2	Gene:	AT2G40700 / 818665	AraportID:	AT2G40700	Length:	610	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	150/599 - (25%)
Similarity:	256/599 - (42%)	Gaps:	103/599 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FHELELDQRILKAVAQ-LGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNS 74
            |..|.||.::...:.: :|::.|||:|:.|||::|.|:||:|.|.||:|||..|..|||..:...
plant    32 FSSLGLDTKLSDQLKERMGFEAPTLVQAQAIPVILSGRDVLVNAPTGTGKTIAYLAPLIHHLQGH 96

  Fly    75 KLNASEQY-VSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALSESPDI 138
            .......: ..|:|:.||:|||.|..:.:|:|:.....:  |............::..|.:...|
plant    97 SPKVDRSHGTFALVIVPTRELCLQVYETLEKLLHRFHWI--VPGYVMGGEKKAKEKARLRKGISI 159

  Fly   139 VVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHL--------------P 189
            ::|||..||.:.:..:....|::..::.||||.:...||.|:.:::||.|              |
plant   160 LIATPGRLLDHLKNTASFVHKNLRWVIFDEADSILELGYGKEIEQIIKLLGSGQNEQGEEDDIVP 224

  Fly   190 PIYQA--VLVSATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQRILAEENDKPAILYALL 252
            ...|.  :|:||||.|.|..:..|.|::||.:.|:..:|  |..||.:...|.::|...::..:.
plant   225 KGIQKQNLLLSATLNDKVNDLAKLSLDDPVMIGLDNTKL--QQNLSIESPAAPDSDAEDMVIHVN 287

  Fly   253 K-------------------LRLIRGKSIIFVNSI-------DRCYKVRLFLEQFGIRACVLNSE 291
            |                   ||:..|..::.:.|:       :...||.:|   |..|..|
plant   288 KSANPLSEDYGIPSQLVQRYLRVPCGARLVALLSVLKNLFEREASQKVVVF---FSTRDAV---- 345

  Fly   292 LPANIRIHTISQF---------NKGTYDIIIASDEHH----MEKPGGKSATNR-KSPRSGDMESS 342
               :.....:|:|         .:||.::.:......    ||:...:||... |:.:...:.|:
plant   346 ---DFHYSLLSEFQWPPNSETEEEGTKELFLKCKTFRLHGSMEQEDRRSAFGTFKTEKQAVLLST 407

  Fly   343 --ASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVS------MKESK-----V 394
              |:||:||..|..:|.:|.|.:.|.|:||.|||||...||..|.|:.      :||.|     :
plant   408 DVAARGLDFPKVRCIIQYDCPGEATEYVHRVGRTARIGEKGEALLFLQPIEIDYLKELKKHGASL 472

  Fly   395 NDSVEKKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQDCWRAATRVAVHDTRIREIKIEILNC 459
            .:....|:.|.|........||    |:..:||..      |..:.:.|:......|.|::.|
plant   473 TEYPLMKVLDKFPIPGNMPRIK----KVLSLESHP------WVISLQRALESLTYAEPKMKSL-- 525

  Fly   460 EKLKAFFEENKRDLQALRHDKPLRAIKV--QSHLSDMPEYIVPKALKRVVGTSSSPVGASEAKQP 522
              .|..|....|...|  |...|::|.|  :.||..:.:....:....:||.|.........:..
plant   526 --AKNAFVSWVRGYAA--HKGELKSIFVVKKLHLGHVAKSFALREQPSLVGKSHHKETMKRKRDE 586

  Fly   523 RQSAAKAAFERQVN 536
            ||...:....::::
plant   587 RQKGQQGKKRKKMS 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	69/226 (31%)
		DEXDc	24..231	CDD:214692	68/224 (30%)
		HELICc	234..386	CDD:238034	44/193 (23%)
AT2G40700	NP_181602.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920