Protein Alignment Hlc and Ddx51

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_081432.2
• Gene: Ddx51 / 69663
• MGIID: 1916913
• Length: 639
• Species: Mus musculus
• Alignment Length: 499
• Identity: 113/499 - (22%)
• Similarity: 205/499 - (41%)
• Gaps: 125/499 - (25%)

  Fly    35 IQSTAIPLLLEG--------------KDVVVRARTGSGKTATYALPLIQKILNSKLNASEQYVSA 85
            :|:..||.|||.              .|:.|.|.||||||..:.:|::|.:|:..:    .::.|
Mouse   196 VQAAVIPALLESADHGFLIGRGGYQPSDLCVSAPTGSGKTLAFVIPVVQALLHRVV----CHIRA 256

  Fly    86 VVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALSES-------PDIVVATP 143
            :|:.|||||.:|..||.....::  ..:|||.:....:....|...:.::       .|||||||
Mouse   257 LVVLPTKELAQQVSKVFNIYTDT--TPLRVALVTGQKSLAKEQESLVQKTADGFRCLADIVVATP 319

  Fly   144 ANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRL------------------------ 184
            ..|:.:.:......|:.:..|::||||.:....::....|:
Mouse   320 GRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFYSEGPTGSCALLQRTQPQA 384

  Fly   185 -------IKHLPPIYQAVLVSATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQ----------- 231
                   :..:|  .|.:|.|||||.|..:::.|.|..|........:..|:|.
Mouse   385 LTAASTCVPQMP--LQKLLFSATLTQDPEKLQRLGLYQPRLFSTRLGQQSPKDTAEVDENSGKYT 447

  Fly   232 ----LSHQRILAEENDKPAILYALLKLRLIRGKSIIFVNSIDRCYKVRLFLEQF-GIRACVLNSE 291
                |:|..:....:.||.|:..|: ||:...:::.|.||.:..:::.|..:.| |:.....:|.
Mouse   448 FPVGLTHHYVPCRLSSKPLIVLHLV-LRMSCSRALCFTNSRENSHRLYLLAQAFGGVSVAEFSSR 511

  Fly   292 LPANIRIHTISQFNKGTYDIIIASDEHHMEKPGGKSATNRKSPRSGDMESSASRGIDFQCVNNVI 356
            .....|...:.||.:|...::|::|                         :.:||||.|.|..||
Mouse   512 YGPGQRKKILKQFEQGKIQLLISTD-------------------------ATARGIDVQGVELVI 551

  Fly   357 NFDFPRDVTSYIHRAGRTARGNNKGSVLS-FVSMKESKVNDSVEKKLCDSFAAQEGEQIIKNYQF 420
            |:|.|:.:.:|:||.|||||....|...: .:.::|.|....|         ::.|...:.:::.
Mouse   552 NYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERKFLQMV---------SEAGVPELTHHEI 607

  Fly   421 KMEEVESFRYRAQDCWRAATRVAVHDTRIREIKIEILNCEKLKA 464
            ..:.::..             ||.::|.:.:::..:...:||||
Mouse   608 PRKLLQPL-------------VARYETALSQLEKTVKEEQKLKA 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	59/236 (25%)
		DEXDc	24..231	CDD:214692	60/247 (24%)
		HELICc	234..386	CDD:238034	40/153 (26%)
Ddx51	NP_081432.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131
		PRK11192	176..639	CDD:236877	113/499 (23%)
		P-loop_NTPase	176..421	CDD:304359	58/232 (25%)
		Q motif	193..201		1/4 (25%)
		DEAD box	343..346		2/2 (100%)
		Helicase_C	462..573	CDD:278689	38/136 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010