Protein Alignment Hlc and ddx10

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_001922220.1
• Gene: ddx10 / 569118
• ZFINID: ZDB-GENE-071022-2
• Length: 864
• Species: Danio rerio
• Alignment Length: 552
• Identity: 137/552 - (24%)
• Similarity: 239/552 - (43%)
• Gaps: 120/552 - (21%)

  Fly     6 QKTVQFHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQK 70
            ::.|:|.:..|.::.||.:.:..::|||.||...|...|:|:||:..|:||||||..:.:|:::.
Zfish    67 KEAVKFSDFPLSKKTLKGLLEAQYRQPTEIQRQTIGFALQGRDVLGAAKTGSGKTLAFLIPVLEC 131

  Fly    71 ILNSKLNASEQYVSAVVLAPTKELCRQSRKVIEQLVE----SCGKVVRVADIADSSNDTVTQRHA 131
            :...:..|.:. :.|::::||:||..|:.:|:.::.:    |.|.|:...|:.|.|...
Zfish   132 LYREQWTAMDG-LGALIISPTRELAYQTFEVLRKVGKNHEFSAGLVIGGKDLKDESEKI------ 189

  Fly   132 LSESPDIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVL 196
              ...:|::.||..||.:.:..:......:..||:||||.:...|:......::::||...|.:|
Zfish   190 --HRTNIIICTPGRLLQHMDETATFHASDLHMLVLDEADRILDMGFADTLNAIVENLPKSRQTLL 252

  Fly   197 VSATLTDDVVRMKGLCLNNPVTLKL-EEPELVPQDQLSHQRILAEENDKPAILYALLKLRLIRGK 260
            .|||.|..|..:..|.|.:|..:.: |:.:......|....::.|.:.|..:||:.|:..|.:..
Zfish   253 FSATQTRSVKDLARLSLKDPEYVWVHEQAKFSTPATLEQNYVVCELHQKVNMLYSFLRSHLQKKI 317

  Fly   261 SIIFVNSIDRCYKVRLFLE-QFGIRACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPG 324
            .:.|....:..|..|:|.. :.||....|:.:.....|:...:.|.:.|..::.|:|
Zfish   318 IVFFACCKEVQYLFRIFCRLRPGISVLALHGKQQQMKRVEVYNDFVRKTSAVLFATD-------- 374

  Fly   325 GKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSM 389
                             .|:||:||..||.|:.||.|.|..:||||.|||||....|..|..:..
Zfish   375 -----------------IAARGLDFPAVNWVLQFDCPEDANTYIHRVGRTARYKEGGEALLVLLP 422

  Fly   390 KESK-----------------VND----SVEKKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQ 433
            .|.|                 ||.    ||::|| ::|.|||.||               :.|||
Zfish   423 SEEKGMISQLQEKKVPINKIQVNPEKLMSVQQKL-EAFLAQEKEQ---------------KERAQ 471

  Fly   434 DCWRAATRVAVHDTRIREIKIEILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQSHLSDMPEYI 498
            .|:.:..|                     ..:..:||.....|:       :|       :|||.
Zfish   472 RCFVSYLR---------------------SVYLMKNKDVFDVLQ-------LK-------LPEYA 501

  Fly   499 VPKALKRVVGTSSSP--VGASEAKQPRQSAAK 528
            :.      :|.:.:|  ....:|:|.|::||:
Zfish   502 MS------LGLAVAPRVRFLLKAQQQRRTAAQ 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	60/212 (28%)
		DEXDc	24..231	CDD:214692	57/211 (27%)
		HELICc	234..386	CDD:238034	41/152 (27%)
ddx10	XP_001922220.1	DEADc	72..276	CDD:238167	60/212 (28%)
		DEXDc	90..275	CDD:214692	56/193 (29%)
		HELICc	289..419	CDD:238034	42/154 (27%)
		DUF4217	452..511	CDD:290667	22/115 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920