Protein Alignment Hlc and ddx1

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001184253.1
• Gene: ddx1 / 556790
• ZFINID: ZDB-GENE-041001-215
• Length: 740
• Species: Danio rerio
• Alignment Length: 655
• Identity: 126/655 - (19%)
• Similarity: 205/655 - (31%)
• Gaps: 303/655 - (46%)

  Fly    11 FHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNS- 74
            |.|:.:...|.:||.::.|..||.||:.:|||:|.|.||::.|.||||||..:::|:||.:..:
Zfish     4 FGEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYETI 68

  Fly    75 -----------------------KLNASEQYVSAVVLAPTKELCRQSR----------------- 99
                                   ::|..::  |......:..||.|||
Zfish    69 KDLQEGKKGRSAVKTGGAVFSKWQMNPFDR--STAFAIGSDGLCCQSREFKEWHGCRTTKAVTKG 131

  Fly   100 ----------------------------------------------------------------- 99
                                                                             
Zfish   132 RYYYEVACHDQGLCRVGWSTAQASLDLGTDKYGFGFGGTGKKSHNKQFDSYGEEFTMHDTIGCYI 196

  Fly   100 --------------------KVIEQL-----VESC------------------------------ 109
                                ::.:||     ..||
Zfish   197 DLEKGHVSFSKNGNDLGLAFEIPQQLRSQPFFASCVLKNAELKFNFGDEAFKHQPKDGYVALNQA 261

  Fly   110 --GKVV--------RVADIADSSN---------------DTVT---------------------- 127
              |.||        :|..:..|||               .|:.
Zfish   262 PEGHVVKSSQTGSAKVTQVKSSSNAPRALIIEPSKELAEQTLNNVNQFKKYVDNPKLRELLIIGG 326

  Fly   128 -----QRHALSESPDIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKH 187
                 |.:.|....||||.||..|......|. :||..|..||:||.|.:.:.|......|:...
Zfish   327 VAAKEQLNVLESGVDIVVGTPGRLDDLISTGK-LDLSQVRFLVLDECDGLLSAGNTDFIMRIYNQ 390

  Fly   188 LPPI------YQAVLVSATL-TDDVVRMKGLCLNNPVTLKLEEPELVPQ-------------DQL 232
            :|.:      .|.::.|||| :.||.::....::.|..:.|:..:.||:             |:|
Zfish   391 IPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPETVHHVVVTVNPKNDKL 455

  Fly   233 ------SHQR---ILAEENDKPA------------ILYALLKLRLIR----GKSIIFVNSIDRCY 272
                  :|.|   :.|:::.:|.            ||.....:|.|:    .::|||..:...|.
Zfish   456 WERLGKNHIRTDEVHAKDDTRPGANSPEMWSEAIKILKGEYTVRAIKEHKMDQAIIFCRTKIDCD 520

  Fly   273 KVRLFLEQFGIR------------ACV-LNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPG 324
            .    :||:.|:            :|| |:.:...|.|.:.:.:|.|.....:|.:|
Zfish   521 N----MEQYFIKQGGGPDKKGHQFSCVCLHGDRKPNERKYNLERFKKQEVKFLICTD-------- 573

  Fly   325 GKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSM 389
                             .|:||||.:.|..|||...|.:..:|:||.||..|.:..|..:|.|:|
Zfish   574 -----------------VAARGIDVRGVPYVINVTLPDEKENYVHRIGRVGRADRMGLAISLVAM 621

  Fly   390 KESKV 394
            ::.||
Zfish   622 EKEKV 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	75/428 (18%)
		DEXDc	24..231	CDD:214692	74/439 (17%)
		HELICc	234..386	CDD:238034	41/183 (22%)
ddx1	NP_001184253.1	SrmB	1..>62	CDD:223587	25/57 (44%)
		P-loop_NTPase	4..>70	CDD:304359	27/65 (42%)
		SPRY_DDX1	93..245	CDD:293933	11/153 (7%)
		DEXDc	238..439	CDD:214692	39/201 (19%)
		P-loop_NTPase	266..426	CDD:304359	35/160 (22%)
		Helicase_C	493..609	CDD:278689	33/144 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010