Protein Alignment Hlc and ddx18

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001016776.1
• Gene: ddx18 / 549530
• XenbaseID: XB-GENE-6085268
• Length: 640
• Species: Xenopus tropicalis
• Alignment Length: 501
• Identity: 133/501 - (26%)
• Similarity: 220/501 - (43%)
• Gaps: 123/501 - (24%)

  Fly    16 LDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNSKLNASE 80
            :::..|:||.::|:...|.||..||..||||:||:..||||||||..:.:|.|:.:...|. ...
 Frog   154 VNENTLRAVTEMGFTHMTEIQHKAIRPLLEGRDVLAAARTGSGKTLAFLIPAIELVYKLKF-MPR 217

  Fly    81 QYVSAVVLAPTKELCRQSRKVIEQL----VESCGKVVRVADIADSSNDTVTQRHALSESPDIVVA 141
            .....::|:||:||..|:..|:::|    |.:.|.:     :..|:.....|:  |:...:||||
 Frog   218 NGTGVLILSPTRELAMQTYGVLKELMAHHVHTFGLI-----MGGSNRSAEAQK--LANGVNIVVA 275

  Fly   142 TPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVLVSATLT---D 203
            ||..||.:.:.......|:::.||:||||.:...|:|::.|::|..||...|.:|.|||.|   :
 Frog   276 TPGRLLDHMQNTPGFMYKNLQCLVIDEADRILEVGFEQEMKQIINLLPKRRQTMLFSATQTRKVE 340

  Fly   204 DVVRMKGLCLNNPVTLKLEEP---------ELVPQDQLSHQRILAEENDKPAILYALLKLRLIRG 259
            |:.|         ::|| :||         |....|.|....::.....:..:|:..|| :..:.
 Frog   341 DLAR---------ISLK-KEPLYVGVDDHKETATVDGLEQGYVVCPSEKRFLLLFTFLK-KNRKK 394

  Fly   260 KSIIFVNSIDRCYKVRLFLEQFGIRACVLN-SELPANIRIH----------TISQFNKGTYDIII 313
            |.::|.:|   |..|:...|       :|| .:||. :.||          |..||......|::
 Frog   395 KMMVFFSS---CMSVKYHYE-------LLNYIDLPV-MAIHGKQKQTKRTTTFFQFCNAESGILL 448

  Fly   314 ASDEHHMEKPGGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARG- 377
            .:|                         .|:||:|...|:.::.:|.|.|...||||.||||||
 Frog   449 CTD-------------------------VAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGI 488

  Fly   378 NNKGSVLSFVSMKE---------------------SKVNDSVEKKLCDSFAAQEGEQII-KNYQF 420
            :.:|..|..:..:|                     ||::| ::.:|         |::| |||..
 Frog   489 DGRGHALLILRPEELGFLRYLKQAKVPLSEFEFSWSKISD-IQTQL---------EKLIEKNYYL 543

  Fly   421 KMEEVESFRYRAQDCWRAATRVAVHDTRIREIKIEILNCEKLKAFF 466
            ...        ||:.::|..|.....:..:...:..||..|:...|
 Frog   544 HKS--------AQEAYKAYIRAYDSHSHKQIFDVNTLNLPKVAISF 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	68/210 (32%)
		DEXDc	24..231	CDD:214692	71/222 (32%)
		HELICc	234..386	CDD:238034	40/163 (25%)
ddx18	NP_001016776.1	SrmB	145..634	CDD:223587	133/501 (27%)
		DEADc	147..354	CDD:238167	72/217 (33%)
		HELICc	368..497	CDD:238034	41/165 (25%)
		DUF4217	529..587	CDD:290667	14/70 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010