Protein Alignment Hlc and Rs1

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001286188.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 147/560 - (26%)
• Similarity: 250/560 - (44%)
• Gaps: 89/560 - (15%)

  Fly     3 QMTQKTVQFHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPL 67
            :..::...|:::.|.:.:::|:..||:..||.||::.||:.|.|:|:...|.||:||||.|.||.
  Fly   151 EANEQITSFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPT 215

  Fly    68 IQKILNSKLNASEQYVSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHAL 132
            ::::|...|| ::.....:||.||:||..|..:|.:||   |........:|....|...|...|
  Fly   216 LERLLYRPLN-NKAITRVLVLVPTRELGAQVYQVTKQL---CQFTTIDVGLAIGGLDVKAQEAVL 276

  Fly   133 SESPDIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVLV 197
            .::||||:|||..|:.:.:......|..:|.|::||||.:....:.:..|.:|.......|.:|.
  Fly   277 RQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTMLF 341

  Fly   198 SATLTDDVVRMKGLCLNNPVTLKLEEPELVP----QDQLSHQRILAE-ENDKPAILYALLKLRLI 257
            |||:::.|..:..:.|:.|:.:.:...:.|.    |:.:   ||..: |.|:..||.:|: .|..
  Fly   342 SATMSEQVKDLAAVSLDKPIKVFVNNNQQVAFNLRQEFI---RIREDKEGDREPILASLI-CRTF 402

  Fly   258 RGKSIIFVNSIDRCYKVRLFLEQFGIRACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHMEK 322
            ....::||.:..:.:::.:.|...|:||..|:..|....|:.::.:|.:...|::||:|
  Fly   403 HDHCMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATD------ 461

  Fly   323 PGGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFV 387
                               .|:||:|...|..||||..|.....||||.|||||....|..:|..
  Fly   462 -------------------VAARGLDIVGVKTVINFVMPITTEHYIHRVGRTARAGRAGISVSLA 507

  Fly   388 SMKESKVNDSVEKKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQDCWRAATRVAVHDTRIREI 452
            ..||.|:...:.|         ..|..|||.....|.:|.:|                 .::..:
  Fly   508 GEKERKIVKDIIK---------NAESTIKNRIIPPEIIEKYR-----------------NKLTSL 546

  Fly   453 KIEILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQSHLSDMPEYIVPKALKRVVGTSSSPVGAS 517
            :.||.|      ..:|.:.:.|         ..|.:..||        |..::::|.::...|..
  Fly   547 EPEIQN------ILDEEQAERQ---------LAKTEQQLS--------KTERKLLGQTNERRGWF 588

  Fly   518 EAKQPRQSAAKAAFERQVNDPLMASQVDFGKRRPAHRRKK 557
            :.||.|: |.|........|...||. ..||.:.|.:||:
  Fly   589 QTKQQRE-AEKDRLALTTGDEDKASG-GKGKGKTAGKRKR 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	67/208 (32%)
		DEXDc	24..231	CDD:214692	66/210 (31%)
		HELICc	234..386	CDD:238034	42/152 (28%)
Rs1	NP_001286188.1	PTZ00424	148..537	CDD:185609	121/427 (28%)
		DEADc	159..364	CDD:238167	67/208 (32%)
		Helicase_C	393..498	CDD:278689	37/130 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451706
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940