Protein Alignment Hlc and pit

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 140/550 - (25%)
• Similarity: 245/550 - (44%)
• Gaps: 101/550 - (18%)

  Fly    16 LDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNSKLNASE 80
            :.:..|:|:.::|:.:.|.|||.::..||:|:|:|..|:||||||..:.:|.:: ::|.......
  Fly   194 VSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVE-LINKLRFMPR 257

  Fly    81 QYVSAVVLAPTKELCRQSRKVIEQLV----ESCGKVVRVADIADSSNDTVTQRHALSESPDIVVA 141
            .....::::||:||..|:..|:::|:    .:.|.|:      ..||..| :...|.:..:|:||
  Fly   258 NGTGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVM------GGSNRQV-ESEKLGKGINILVA 315

  Fly   142 TPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVLVSATLTDDVV 206
            ||..||.:.:.......|:::.|::||.|.:...|:|::.|::|..||...|.:|.|||.|..:.
  Fly   316 TPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTARIE 380

  Fly   207 RMKGLCL-NNPVTLKL-EEPELVPQDQLSHQRILAEENDKPAILYALLKLRLIRGKSIIFVNSID 269
            .:..|.| :.|:.:.: :..:....|.|....|:.....:..:|:..|| :..:.|.::|.:|
  Fly   381 ALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEKRLLVLFTFLK-KNRKKKVMVFFSS-- 442

  Fly   270 RCYKVRLFLEQFG---IRACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPGGKSATNR 331
             |..|:...|.|.   :....::.:.....|..|..||......|::.:|
  Fly   443 -CMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTD--------------- 491

  Fly   332 KSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNN---------KGSVLSFV 387
                      .|:||:|...|:.::.:|.|.|...||||.||||||:.         :...|.|:
  Fly   492 ----------VAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFL 546

  Fly   388 S-MKESKVN-DSVE---KKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQDCWRAATRVAVHDT 447
            . :|.:||. :..|   :|:.| ...|..:.|.|||.......|:|:          :.|..:|:
  Fly   547 RYLKAAKVPLNEFEFSWQKIAD-IQLQLEKLIAKNYFLNQSAKEAFK----------SYVRAYDS 600

  Fly   448 RIREIKIEILNCEKLKAFFEENKRDLQALRHD-----KPLRAIKVQSHLSDMPEYIVPKALKRVV 507
                        .:||..|..|..||||:...     .|:..:||.:...:.||       |||.
  Fly   601 ------------HQLKQIFNVNTLDLQAVAKSFGFLVPPVVDLKVGAAKRERPE-------KRVG 646

  Fly   508 GTSSSPVGASEAKQPRQ-SAAKAAFERQVN 536
            |.     |....|:..: ||:|....:|||
  Fly   647 GG-----GFGFYKKMNEGSASKQRHFKQVN 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	61/208 (29%)
		DEXDc	24..231	CDD:214692	59/212 (28%)
		HELICc	234..386	CDD:238034	36/163 (22%)
pit	NP_001287459.1	SrmB	186..677	CDD:223587	139/549 (25%)
		DEADc	187..394	CDD:238167	61/207 (29%)
		HELICc	408..537	CDD:238034	36/157 (23%)
		DUF4217	569..627	CDD:290667	17/79 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040