Protein Alignment Hlc and CG9630

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_649777.1
• Gene: CG9630 / 40974
• FlyBaseID: FBgn0037561
• Length: 613
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 149/613 - (24%)
• Similarity: 247/613 - (40%)
• Gaps: 138/613 - (22%)

  Fly    16 LDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNSKLNAS- 79
            |...:|:.|...|:||.|.:|:.||||||..|||...|.||||||..:.:|::: ||..:...:
  Fly    14 LSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLE-ILQRRHKETP 77

  Fly    80 --EQYVSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALS--------E 134
              .:.:.|:|::||:||.||..:|:.|.:|.       .|:...:...:...:::.        |
  Fly    78 WGPKEIGALVISPTRELARQISEVLAQFLEH-------EDLEHLNQQLIVGGNSIEEDIATLRRE 135

  Fly   135 SPDIVVATPANLL-AYAEAGSVVDL----KHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQA 194
            :|.|:|.||..|. .:...|..::|    |.:|.||:||||.:...|::.....::.:||...:.
  Fly   136 TPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRT 200

  Fly   195 VLVSATLTDDVVRMKGLCLNNPVTLKLEEPELV--PQDQLSHQRILAEENDKPAILYALLKLRLI 257
            .|.|||.|.:|..:....|.|||.:.::|...|  |....:..||:..|....|:|..|.....:
  Fly   201 GLFSATQTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEFLSSPATV 265

  Fly   258 RGKSIIFVNSIDRCYKVRLFLEQFGIRACV------LNSELP-----------ANIRIHTISQFN 305
            .||.::|                |...|||      |...||           .|.|.:.:.:|.
  Fly   266 IGKVMVF----------------FPTCACVEYWAEALPPLLPKRTVLGIHGKMKNKRANVVEKFR 314

  Fly   306 KGTYDIIIASDEHHMEKPGGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHR 370
            .....:::.:|                         ..:||:|...:..|:.:|.|...:|::||
  Fly   315 NTPQAVLLCTD-------------------------VLARGLDVPEIEWVVQWDPPSTASSFVHR 354

  Fly   371 AGRTARGNNKGSVLSFVSMKES------KVNDSVEKKLCDSFAAQEGEQIIKNYQFKMEEVESFR 429
            .|||||..|:|:.|.|:...|.      |:|..||.....:..|::.::..|.....::::.  |
  Fly   355 VGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLH--R 417

  Fly   430 YRAQDCWRAATRVAVHDTRIREIKIEILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQS----- 489
            .:|.|       ..|:|..:|..      ...::|:   .|.:..|:...|.|...|:.:
  Fly   418 LQAAD-------KGVYDKGMRAF------VSHVRAY---TKHECSAILRLKDLDLGKMATAYGLL 466

  Fly   490 HLSDMPE--------YIVP------------KALKRVVGTSSSPVGASEAKQPRQSAAKAAFERQ 534
            .|..|||        |:.|            .|.|..|..............|.|...|...|..
  Fly   467 QLPRMPELKNYQGGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGSWPGQKQHKKRVESW 531

  Fly   535 VNDPLMASQVDFGKR---RPAHRRKKKA 559
              |....:::|...:   |.|.:::|||
  Fly   532 --DQTKKAKLDAKSKKELRKAKKQRKKA 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	69/219 (32%)
		DEXDc	24..231	CDD:214692	70/224 (31%)
		HELICc	234..386	CDD:238034	37/168 (22%)
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	69/219 (32%)
		DEXDc	22..232	CDD:214692	68/217 (31%)
		HELICc	239..370	CDD:238034	37/171 (22%)
		DUF4217	411..470	CDD:290667	13/76 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451677
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950