Protein Alignment Hlc and CG7878

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 114/437 - (26%)
• Similarity: 202/437 - (46%)
• Gaps: 72/437 - (16%)

  Fly    20 ILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALP-LIQKILNSKLNASEQYV 83
            :|:.:.::|:.:|:.|||.|.|:||:|.|::..|:||:|||..:.|| :|.....|....:....
  Fly   294 MLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRGGA 358

  Fly    84 SAVVLAPTKELCRQSRKVIEQLVESCG-KVVRVADIADSSNDTVTQRHALSESPDIVVATPANLL 147
            :.:|||||:||..|    ||..|:... :.::...:....|..: |...|....:|::.||..|.
  Fly   359 NVLVLAPTRELALQ----IEMEVKKYSFRGMKAVCVYGGGNRNM-QISDLERGAEIIICTPGRLN 418

  Fly   148 AYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVLVSATLTDDVVRMKGLC 212
            ....| :|:|:..:..||:||||.:...|:|...::::..:.|..|.::.|||....|.|:....
  Fly   419 DLIMA-NVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSY 482

  Fly   213 LNNPVTLKLEEPELVPQDQLSH-QRILAEENDKPAILYALLKLRLIRGKSIIFVNSIDRCYKVRL 276
            :.||:.:.:...:|.....:.. .:::.::.||...:.:.:|......|.|||      |.:
  Fly   483 MKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIF------CGR--- 538

  Fly   277 FLEQFGIRACVLNSELPAN--------------IRIHTISQFNKGTYDIIIASDEHHMEKPGGKS 327
                 .:||..|:|||..:              .|...|:....|...|::|:|
  Fly   539 -----KVRADDLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATD----------- 587

  Fly   328 ATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKES 392
                          .||||:|.:.:.:|||:|||.::..|:||.|||.|...:|:.:||.:.::.
  Fly   588 --------------VASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFTREDW 638

  Fly   393 KVNDSVEKKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQDCWRAA 439
                ::.|:|.:  ..||.||.:.:....|..    |::|....|||
  Fly   639 ----AMAKELIE--ILQEAEQEVPDELHNMAR----RFKAMKDKRAA 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	60/201 (30%)
		DEXDc	24..231	CDD:214692	60/208 (29%)
		HELICc	234..386	CDD:238034	39/166 (23%)
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	60/200 (30%)
		DEXDc	298..505	CDD:214692	60/212 (28%)
		Helicase_C	514..624	CDD:278689	38/148 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930