Protein Alignment Hlc and mus301

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 112/619 - (18%)
• Similarity: 212/619 - (34%)
• Gaps: 161/619 - (26%)

  Fly    29 WQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNSKLNA--SEQYVSAV----- 86
            ||...|    .:|.:.:.|:::....|..|||....:.:::::|..:.|.  ...|||.|
  Fly   267 WQDECL----NLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVS 327

  Fly    87 VLAPTKELCRQSRKVIEQLVESCGK----------------VVRVADIADSSND----------T 125
            .::|   .......::|:.....||                :.:.|.:.||..|          .
  Fly   328 AMSP---FAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVV 389

  Fly   126 VTQRHALSESP---------DIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEK-D 180
            |.:.|.:.|..         ..|:...||:.....:.::.:|..:.:.:  .|| |:..|:.. :
  Fly   390 VDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFL--NAD-VYTRGFRPVE 451

  Fly   181 FKRLIKHLPPIYQAVLVSATLTDDVVRMKGLCLNNPVTLKLEEPE----LVPQDQLSHQRILAEE 241
            .|..||..|.:.:......||.:..|..:.:..|....:|..:|:    |:.:....|..::...
  Fly   452 LKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCP 516

  Fly   242 NDKPAILYALLKLRLI---------RGKSIIFVNSIDR-CYKVRLFLEQFGIRACVLNSELPANI 296
            :.|.....|||..|::         |.:.:..::::|: |          ||.:.||...||..|
  Fly   517 SRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMC----------GILSPVLAKTLPYGI 571

  Fly   297 RIHTISQFNKGTYDIIIASDEHHMEKPGGKSATNRK----SPRSGDM-----ESSASRGIDFQCV 352
            ..                   ||    .|.:...||    :.|.|.:     .|:.:.|::....
  Fly   572 AY-------------------HH----SGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAK 613

  Fly   353 NNVINFDFPRD----VTSY---IHRAGRTARGNNKGSVLSFVSMKESKVN-----------DSVE 399
            ..:|...:...    :..|   :.||||...|....|:|    :.:||.|           |...
  Fly   614 RVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESIL----IAQSKDNLLVGQMLFSPMDKAL 674

  Fly   400 KKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQDCWRAATRVAVHDTRIREIKIEILNCEKLKA 464
            ..|..:.|......|:......:.|......|..:....:.:....:..:.||.:.||. |..|
  Fly   675 SSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILR-EMFK- 737

  Fly   465 FFEENKRDLQALRHDKPLRAIKVQSH----LSDMPEYIVPKALKRVVGTSSSPVGASEAKQPRQS 525
                ||    .|:..:|....|:.|.    ..|:.:...|...:|::...|:|...:       :
  Fly   738 ----NK----VLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLT-------N 787

  Fly   526 AAKAAFERQVNDPLMASQVDFGKRRPAHRRKKKA 559
            ..:|||:         :.:|:.:....|:..|:|
  Fly   788 IGRAAFK---------AGIDYKRANAIHKELKQA 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	42/233 (18%)
		DEXDc	24..231	CDD:214692	45/248 (18%)
		HELICc	234..386	CDD:238034	34/177 (19%)
mus301	NP_648178.1	BRR2	247..998	CDD:224125	112/619 (18%)
		DEXHc_POLQ-like	247..449	CDD:350784	34/191 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100