Protein Alignment Ddx56 and eIF4A

DIOPT Version :10

• Sequence 1: NP_523434.2
• Gene: Ddx56 / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 405
• Identity: 107/405 - (26%)
• Similarity: 205/405 - (50%)
• Gaps: 65/405 - (16%)

  Fly    11 FHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKILNSK 75
            |.::.|.:.:|:.:...|:::|:.||..||...:.|:||:.:|::|:|||||:::.::|:|
  Fly    32 FDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQI---- 92

  Fly    76 LNASEQYVSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALSESP-DIV 139
             :.|.:...|::||||:||..|    |:::|.:.|:.::|...|......|.:...:.||. .:|
  Fly    93 -DTSIRECQALILAPTRELATQ----IQRVVMALGEYMKVHSHACIGGTNVREDARILESGCHVV 152

  Fly   140 VATPANLLAYAEAGSVVDL--------KHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVL 196
            |.||         |.|.|:        ::::..|:||||.:.:.|::...:.:.|.|||..|.:|
  Fly   153 VGTP---------GRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVIL 208

  Fly   197 VSATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQRILAEENDKPAI---LYALLKLRLIR 258
            :|||:..||:.:....:.:||::.:::.||..:........:.:||.|...   ||..|.:.
  Fly   209 LSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSIT--- 270

  Fly   259 GKSIIFVNS---IDRCYKVRLFLEQFGIRACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHM 320
             :|:||.|:   :|:..: .:.:..|.:.|  ::.::....|...:.||..|:..::|.:|
  Fly   271 -QSVIFCNTRRKVDQLTQ-EMSIHNFTVSA--MHGDMEQRDREVIMKQFRSGSSRVLITTD---- 327

  Fly   321 EKPGGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLS 385
                                 ..:||||.|.|:.|||:|.|.:..:||||.||..|...||..::
  Fly   328 ---------------------LLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAIN 371

  Fly   386 FVSMKESKVNDSVEK 400
            |::..:.::...:|:
  Fly   372 FITDDDRRILKDIEQ 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx56	NP_523434.2	DEADc_DDX56	16..221	CDD:350719	63/213 (30%)
		SF2_C_DEAD	232..387	CDD:350174	39/160 (24%)
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	107/405 (26%)