Protein Alignment Hlc and CG8611

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_788922.1
• Gene: CG8611 / 32725
• FlyBaseID: FBgn0027602
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 157/639 - (24%)
• Similarity: 272/639 - (42%)
• Gaps: 141/639 - (22%)

  Fly    15 ELDQRILKAVAQ------------------------LGWQQPTLIQSTAIPLLLEGKDVVVRART 55
            :|.||.:|.|.:                        |..::.|.:|...||.:|:||||:||::|
  Fly   310 QLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQGKDVLVRSQT 374

  Fly    56 GSGKTATYALPLIQKILNSKLNAS-EQYVSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIA 119
            |||||..|||||::.:...:.... :..|.|:|:.||:||..|:.::|::||:....:|..:.:.
  Fly   375 GSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTWIVPGSLLG 439

  Fly   120 DSSNDTVTQRHALSESPDIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRL 184
            ..|..  :::..|.:..:|::.||..|:.:....:...|..::.|::||||.:...|||:|.|:|
  Fly   440 GESRK--SEKARLRKGINILIGTPGRLVDHLLHTASFKLTKLQFLILDEADRLLELGYERDVKQL 502

  Fly   185 I------------KHLPPIYQAVLVSATLTDDVVRMKGLCLNNPVTL----KLEEPELVPQDQLS 233
            :            |.||.: |.:|:|||||..|.::.||.|.||:.:    :.....|..:|...
  Fly   503 VEAIDKQRAECEDKELPQL-QRMLLSATLTSQVQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQ 566

  Fly   234 HQRI---------LAE-ENDKPAIL---------YALL--KLRLIRGKSIIF--VNSIDRCYKVR 275
            .:.|         |.| :.|...:|         |.::  ||||:...|::.  |::..:.:|..
  Fly   567 KETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLAKEVDASPKQFKAI 631

  Fly   276 LFL---EQFGIRACVLNSELPANIRIHTISQFNKGTY----DIIIASDEHHMEKPGGKSATNRKS 333
            :|:   |.......:||..|...: :....:..||..    ||.:.......:..|..:.|.|:.
  Fly   632 VFMSTTEMVNFHHDMLNEALTRRV-LDEEDEQEKGDSDDDGDIPLLQGLRFFKLHGSMTQTERQG 695

  Fly   334 PRSGDMESSA---------SRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSM 389
            ...|..:.::         .||||...:..|:.:..|:....::||.|||||...||..:.|::.
  Fly   696 VFRGFRDCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTP 760

  Fly   390 KESKVNDSVEKKLCDSFAAQEGEQIIKNYQFKMEEVESFRYRAQ--DCWRAATRVAVHDTRIREI 452
            .|::....:|||                           |.|.|  |.:.....:...|...|.:
  Fly   761 SEAQFVRHLEKK---------------------------RIRIQQGDMYAYLQTLLPKDDEARTV 798

  Fly   453 KIEILNCE-KLKAFFEENKRDLQALRHDKPLRAIKVQSHLSDMPEY-IVPKALKRV-------VG 508
            :....|.: |.:...|:: |:|    |||..:|.     :|.|..| ..||.||.:       :|
  Fly   799 QEAASNLQHKFQTLLEDD-REL----HDKSCKAF-----VSWMKFYSTFPKELKPIFNVRIAHMG 853

  Fly   509 TSSSPVGASEAKQPRQSAAKAAFERQVNDPLMASQVDFGKRRP----AHRRKKK 558
            ..:......||  |.:.|||.|..:....   .:::.:.:|.|    |.:|.|:
  Fly   854 HFAKSFALKEA--PSKFAAKHAAPKAAPP---TNRLTYTERDPEKIQAQKRAKR 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	74/245 (30%)
		DEXDc	24..231	CDD:214692	71/247 (29%)
		HELICc	234..386	CDD:238034	41/190 (22%)
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302
		P-loop_NTPase	332..548	CDD:304359	69/218 (32%)
		DEXDc	348..554	CDD:214692	68/208 (33%)
		HELICc	601..757	CDD:238034	36/156 (23%)
		DUF4217	805..866	CDD:290667	18/72 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040