Protein Alignment Hlc and CG32344

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_612028.4
• Gene: CG32344 / 326208
• FlyBaseID: FBgn0052344
• Length: 827
• Species: Drosophila melanogaster
• Alignment Length: 692
• Identity: 169/692 - (24%)
• Similarity: 288/692 - (41%)
• Gaps: 182/692 - (26%)

  Fly     7 KTVQFHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKI 71
            |:..|..:.|...::|.:.:.|::.||.||...|||:|||:|||..|:|||||||.:.:||.:|:
  Fly    37 KSGGFQSMGLGFELIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKL 101

  Fly    72 LNSKLNASEQYVSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTV-TQRHALSES 135
            ...:.....:   |::|:||:||..|:.|.|::|    |:.:.:..|.....|:: :|..|:...
  Fly   102 QRREPTKGAR---ALILSPTRELAVQTYKFIKEL----GRFMELKSILVLGGDSMDSQFSAIHTC 159

  Fly   136 PDIVVATPANLLAYAEAGSVVDLK--HVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVLVS 198
            ||::||||...|.....   :|||  .:|.:|.||||.:|..|:.:.....:..||...|.|:.|
  Fly   160 PDVIVATPGRFLHLCVE---MDLKLNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMFS 221

  Fly   199 ATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQRILAEENDKPAILYALLKLRL-IRGKSI 262
            |||...:|......||:||.::|:....:| |.|:.:.:....:|:...|..|||..: ::.:::
  Fly   222 ATLPKLLVEFARAGLNDPVLIRLDVESKLP-DALALKFLYCRPDDRYTALVVLLKYVIPVQSQTV 285

  Fly   263 IFVNSIDRCYKVRLFLEQFGI-RACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPGGK 326
            :|..:......:...|.:.|| .|.|.:|..||..:|:|....|| ...::|.:|
  Fly   286 VFAGTQHHVELISYILTEAGISNASVYSSLDPAARKINTAKFVNK-KVSVLIVTD---------- 339

  Fly   327 SATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVS--- 388
                           .|:||||...::.|:|..||.....::||.||.||....|:..|.||
  Fly   340 ---------------VAARGIDIPSLDFVVNLHFPGKPKLFVHRVGRCARAGRTGTAYSIVSTDD 389

  Fly   389 ----------------------------------------MKES-------KVNDSVEKKLCDS- 405
                                                    :|:|       :.:::..||...|
  Fly   390 TAHLLDLHLFLNRPFNIHDSSALGTIPQDLLEEEHLTVTDIKKSHHIAGVLRTSENAYKKYLSSR 454

  Fly   406 -FAAQEGEQIIKNYQ-FKMEEVESFRYRAQDCWRAA----------TRVAVHDTRIREIKIEILN 458
             .|:.:....:|..: |.::.:|.|...|....:||          .:|:..:.:::|.|.:||
  Fly   455 PVASTDANARVKKIKFFALKPLEDFFTAAPVLAQAAEASGQSTESQAKVSAAERKLQEEKHDIL- 518

  Fly   459 CEKLKAF------FEEN--KRDLQ-------ALRHDKPLRAIKVQSHLSDMPEY----------- 497
             .|:::|      ||.|  ::..|       .::|.:.:...:.|....|:.|.
  Fly   519 -VKMRSFRPGGTVFELNTTQKSTQFIVMKEKRMQHAEVINKFRQQRAEEDIDEEKKTIEALNPSS 582

  Fly   498 -IVPKALKRVVGTSSSPVGASEAKQ--------------------------PRQSAAKAA----- 530
             .:|.|.:..:.::.:.|.|.:..|                          |.|||.|..
  Fly   583 GRMPTADEEAISSTFNKVVAPKRLQNMDALYKDKPKKKKRKINSKDEDHYVPYQSADKHTEDGLA 647

  Fly   531 ---FERQ-------VNDPLMASQVDFGKRRPA----HRRKKK 558
               ||||       |:|..::.:|   |.:|.    .|.|||
  Fly   648 INNFERQAQNAEFSVSDRDLSQEV---KHKPGLKKWDRIKKK 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	74/211 (35%)
		DEXDc	24..231	CDD:214692	73/209 (35%)
		HELICc	234..386	CDD:238034	36/153 (24%)
CG32344	NP_612028.4	DEADc	41..243	CDD:238167	74/211 (35%)
		DEXDc	54..243	CDD:214692	71/198 (36%)
		HELICc	263..384	CDD:238034	36/146 (25%)
		DBP10CT	666..721	CDD:285373	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940