Protein Alignment Hlc and CG6227

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: CG6227 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 608
• Identity: 140/608 - (23%)
• Similarity: 252/608 - (41%)
• Gaps: 154/608 - (25%)

  Fly     1 MSQMTQKTVQFHELELD----------------------QRILKAVAQLGWQQPTLIQSTAIPLL 43
            :::||...|:.:..:|:                      ::.::.:.:||:::||.||..|||.:
  Fly   480 LTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAI 544

  Fly    44 LEGKDVVVRARTGSGKTATYALPLIQKILNSKLNASEQYVSAVVLAPTKELCRQSRKVIEQLVES 108
            :.|:|::..|:||||||..:.||:.:.||:...........|:::|||:|||.|..|.|.:..:|
  Fly   545 MSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKS 609

  Fly   109 CGKVVRVADIADSSNDTVTQRHA-LSESPDIVVATPANL--LAYAEAGSVVDLKHVETLVVDEAD 170
            .|    :..:.......::::.| |....:|:|.||..:  :..|.:|.|.:|:.|..:|:||||
  Fly   610 LG----LRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEAD 670

  Fly   171 LVFAYGYEKDFKRLIKHLPPIYQAVLVSATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQ 235
            .:|..|:|....|:|.::.|..|.|:.|||....:..:....|..|:.:.:....:|.::...|.
  Fly   671 RMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALARRILKKPIEVIVGGRSVVCKEVEQHV 735

  Fly   236 RILAEENDKPAILYALLKLRLI---RGKSIIFVNSIDR--------------CYKVRLFLEQFGI 283
            .||.::    |..:.||:|..|   .|..|:||:..:.              |..:...::||.
  Fly   736 VILNDD----AKFFKLLELLGIYQEAGSIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFD- 795

  Fly   284 RACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPGGKSATNRKSPRSGDMESSASRGID 348
                         |..||..|..|...::||:                         |.|:||:|
  Fly   796 -------------RDSTIIDFKSGKVRLLIAT-------------------------SVAARGLD 822

  Fly   349 FQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKESKVNDSVEKKL----------- 402
            .:.:..|:|:|.|.....|:||.|||.|...|||..:|::.::|:....:.:.:
  Fly   823 VKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAEL 887

  Fly   403 ----CDSFAAQEGEQII---------KNYQFKMEEVESFRYRAQDCWRAATRVAVHDTRIREIKI 454
                .:..|.||.|...         |.::|..:|..:.: .::...:||..:|..|..
  Fly   888 QALWTEYKALQEAEGKTVHTGGGFSGKGFKFDEQEFNAAK-ESKKLQKAALGLADSDDE------ 945

  Fly   455 EILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQSHLSDMPEYIVPKALKRVVGTSSSPVGASEA 519
                        |:.::|:     |:.:..|               .|.||.|..:|:...|:.|
  Fly   946 ------------EDIEQDI-----DQQIEQI---------------FAAKRTVKDTSAAATAAAA 978

  Fly   520 KQPRQSAAKAAFERQVNDPLMAS 542
            .....:||.||....  :|.:||
  Fly   979 AAAAAAAAAAAVSGA--NPALAS 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	64/233 (27%)
		DEXDc	24..231	CDD:214692	64/209 (31%)
		HELICc	234..386	CDD:238034	41/168 (24%)
CG6227	NP_573020.2	SrmB	482..967	CDD:223587	129/570 (23%)
		DEADc	516..719	CDD:238167	63/206 (31%)
		HELICc	733..860	CDD:238034	41/169 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451472
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030