Protein Alignment Hlc and Ddx31

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001101294.2
• Gene: Ddx31 / 311835
• RGDID: 1304895
• Length: 682
• Species: Rattus norvegicus
• Alignment Length: 606
• Identity: 156/606 - (25%)
• Similarity: 262/606 - (43%)
• Gaps: 143/606 - (23%)

  Fly    11 FHELELDQRILKAV-AQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKI--L 72
            |.||:|...::..: ..|.....|.:|..:||:||||:|.:||::||||||..|.:|::|.:  |
  Rat   105 FQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAL 169

  Fly    73 NSKLNASE-QYVSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALSESP 136
            .||:..|: .|  |:||.||:||..||...:::|::....:  |..:........:::..|.:..
  Rat   170 TSKIQRSDGPY--ALVLVPTRELALQSFDTVQKLLKPFTWI--VPGVLMGGEKRKSEKARLRKGI 230

  Fly   137 DIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQA---VLVS 198
            :|:::||..|:.:.::...:....|..|||||||.:...|:|||...::..:....|.   ||:|
  Rat   231 NILISTPGRLVDHIKSTKNIHFNRVRWLVVDEADRILDLGFEKDVTVILNAVNAECQKRQNVLLS 295

  Fly   199 ATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQRILAEENDKPAI-----LYALL---KLR 255
            ||||:.|.|:..:.|:|||::.:.:..   .||.:.:.:.:.:.|..||     .|.:|   |||
  Rat   296 ATLTEGVTRLADISLHNPVSISVLDKS---WDQPNPKEVASIQLDSFAIPESLDQYVVLVPSKLR 357

  Fly   256 LI--------------RGKSIIFVNSIDRCYKVRLFLEQFGIRACVLNSELPAN----------- 295
            |:              ..|.|:|.:|   |..|......| :...:.:|..||:
  Rat   358 LVCLAAFILKKCKFEKDQKMIVFFSS---CELVEFHYNLF-LHTLLCHSGTPASETLPSASWPLK 418

  Fly   296 -IRIH----------TISQFNKGTYDIIIASDEHHMEKPGGKSATNRKSPRSGDMESSASRGIDF 349
             :|:|          ...:|:.....:::.:|                         .||||:|.
  Rat   419 FLRLHGNMKQEERTSVFHEFSHSGTGVLLCTD-------------------------VASRGLDL 458

  Fly   350 QCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKESK-VNDSVEKKLCDSFAAQEGEQ 413
            ..|..::.:..|.....||||.|||||....||.|..::..|:: ||.....|:..|
  Rat   459 PQVTWIVQYSAPSAPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVS-------- 515

  Fly   414 IIKNYQFKMEEVESFRYRAQDCWRAATRVA--VHDTRIREIKIEILNCEK---LKAFFEENKRDL 473
                 :.|:|.:.:...: .||::...|.|  .|.|..:||:      |:   |:..||:.....
  Rat   516 -----EIKLEGILAVLAK-DDCFKRRQRGAQRSHATGPQEIR------ERATVLQTVFEDYVHSS 568

  Fly   474 QALRHDKPLRAIK-----VQSHLSDMPEYIVPKALKRV-------VGTSSSPVGASEAKQPR--- 523
            |        |.:.     :||.:.....|  ||.||.:       :|..:...|..:|  ||
  Rat   569 Q--------RMVSWAKKALQSFIRAYATY--PKELKSIFHVRSLHLGHVAKSFGLRDA--PRNLG 621

  Fly   524 -QSAAKAAFERQVNDPLMASQ 543
             .:..||:|:|.  ||...:|
  Rat   622 VSAVRKASFKRP--DPRRKTQ 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	72/215 (33%)
		DEXDc	24..231	CDD:214692	68/213 (32%)
		HELICc	234..386	CDD:238034	42/195 (22%)
Ddx31	NP_001101294.2	SrmB	101..635	CDD:223587	153/599 (26%)
		DEADc	105..317	CDD:238167	72/215 (33%)
		HELICc	347..495	CDD:238034	39/176 (22%)
		DUF4217	557..618	CDD:290667	15/72 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010