Protein Alignment Hlc and Y55F3BR.1

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_500004.2
• Gene: Y55F3BR.1 / 176913
• WormBaseID: WBGene00021938
• Length: 728
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 116/641 - (18%)
• Similarity: 191/641 - (29%)
• Gaps: 287/641 - (44%)

  Fly    11 FHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQ------ 69
            |.|..:...:..|::.|.|..||.:||.|||.:|.|.|.::.|.||||||..::||:.|
 Worm     4 FEEFGIIPELSDALSSLNWTLPTAVQSEAIPAILGGADALIAAETGSGKTGAFSLPIAQIVWERR 68

  Fly    70 ----KILNS----------KLNASE---------------------------------------- 80
                |..||          :||..:
 Worm    69 KSAEKSQNSGQKPENSREFQLNREDRDVSLQIDKTGLNCESRVAKEWHGARATAGLYGNGKYYYE 133

  Fly    81 ----------------------------------------------------------------- 80
                                                                             
 Worm   134 VTVTRDGLCRVGWATLSGSLKIGTDFESFGYGGTGKKSFGKKFDDYGTSFTTNDVLGCFLDLDEL 198

  Fly    81 -------------------------------------------------------QYVS------ 84
                                                                   |||:
 Worm   199 KIWWSKNGVQFPVAYQIDKKFKTAATCLYPAILCQNSGLGVNFGGSAAFKYPPGTQYVAVAQAED 263

  Fly    85 --------------------AVVLAPTKELCRQSRKVIE---QLVESCGKVVRVADIADSSNDTV 126
                                .|:|.||:||.:|:.:.|:   .:::|  ..:|...:|...|...
 Worm   264 GNLKWWSAAEQLSIDSSTPLCVILEPTRELVQQTFQNIQTFASVLDS--PKIRCVTLAAGENMNQ 326

  Fly   127 TQRHALSESPDIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFA--YGYEKDFKRLIKHLP 189
            ..| .|....||||.||:.:......|.:. .|:::.:|:||.|...|  .......:.:.:.||
 Worm   327 ILR-TLETGCDIVVGTPSRVFDLIHTGKLA-TKNLQFVVIDEIDQFLAGKNNCAHQIESIFRVLP 389

  Fly   190 PI------YQAVLVSATLTD-DVVRMKGLCLNNPVTLKLEEPELVPQD----------------- 230
            .:      .|.:..||||.: :|.|.....::.|..:.|:..:.|..|
 Worm   390 LVAQDGTRRQVIACSATLHNFEVCRFADRHMSFPQWIDLKGADCVSADVHHVVCHVDASEDKQWI 454

  Fly   231 QLSHQRILAEEN-------------DKPAI---------LYALLKLRLIR-GKSIIFVNSIDRCY 272
            :..||::..|::             ||..|         :|.:..:..:: .|:|:|..:..:|.
 Worm   455 RQMHQQVHLEDDHVHDGDQIRPGTTDKDTISLGTKILKGIYVVRAIHALQMDKAIVFCRTKQQCD 519

  Fly   273 KVRLFLEQFGIRACVLNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPGGKSATNRKSPRSG 337
            .:..||:|..:.|..|:.:..|..|..::..|.||....::.||
 Worm   520 HMEHFLQQNNLSAACLHGDRSAEERQSSLEGFKKGIIRFLVCSD--------------------- 563

  Fly   338 DMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKESK 393
                ..:||:|.|.|..||:...|.:.:.|:||.||..|....|..:|.||..|.|
 Worm   564 ----VVARGLDVQGVPFVISVTLPDEKSMYVHRIGRVGRAERMGLSISLVSEYEEK 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	70/426 (16%)
		DEXDc	24..231	CDD:214692	70/441 (16%)
		HELICc	234..386	CDD:238034	38/174 (22%)
Y55F3BR.1	NP_500004.2	P-loop_NTPase	4..>69	CDD:304359	25/64 (39%)
		SPRY_DDX1	89..244	CDD:293933	2/154 (1%)
		SrmB	278..>614	CDD:223587	81/364 (22%)
		P-loop_NTPase	<282..420	CDD:304359	36/141 (26%)
		Helicase_C	492..599	CDD:278689	30/131 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010