Protein Alignment Hlc and ZK512.2

DIOPT Version :9

• Sequence 1: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001254980.1
• Gene: ZK512.2 / 176292
• WormBaseID: WBGene00013983
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 131/579 - (22%)
• Similarity: 232/579 - (40%)
• Gaps: 126/579 - (21%)

  Fly    43 LLEGKDVVVRARTGSGKTATYALPLIQKILNSKLNASEQYVSAVVLAPTKELCRQSRKVIEQLVE 107
            ||...||||.:.||||||..:.||:::.|.|:||..::  :.|::|:|::|||.|...||:...|
 Worm    43 LLNLSDVVVESPTGSGKTLAFVLPMMRMIQNAKLQPAD--IGALILSPSRELCSQIVSVIQPFAE 105

  Fly   108 SCGKVVRVADIADSSNDTVTQRHAL--------SESPDIVVATPANLLAYAEAGSVV---DLKHV 161
            .....|          :|||....:        :::.:|:||||..|....:....:   .::.:
 Worm   106 KLNLTV----------ETVTGGQKVDKNIKMFKNKNVNILVATPGRLFQIIQHEKTLIARKMRTL 160

  Fly   162 ETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQAVLVSATLT--DDVVRMKGLCLNNPVTLKLEEP 224
            :.||:||||......:|...:.::..:|...:..|.|||..  :|.:.:.||.....|.:..|..
 Worm   161 QLLVIDEADRFNEIQFEDHMREILSCIPKQRRTGLFSATQVKEEDDLMVFGLRNAKQVKVAQERN 225

  Fly   225 ELVPQDQLSHQRILAEENDKPAILYALLKLRLIRGKSIIFVNSIDRCYKVRLFLEQFGIRACV-- 287
            ...| ..|.:..:....::|.::....::.|..: |.:||..|   |..||.|.:.|  ..|:
 Worm   226 SAAP-STLKNYYVECRADEKTSVCLEFIRQRTDK-KILIFFPS---CNSVRYFYKIF--ERCLGK 283

  Fly   288 -----LNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPGGKSATNRKSPRSGDMESSASRGI 347
                 ::.:.....|...|..|:..|..::|::|                         ..:|||
 Worm   284 RPLFAVHGKCSNPHRASQIKAFSDSTNGVMISTD-------------------------VMARGI 323

  Fly   348 DFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKE-SKVN--DSVEKKLCDSFAAQ 409
            |...::.||.||.|:..:.::||||||||...:|:.|..::.:: :.||  |:.||...|..
 Worm   324 DISDIDWVIQFDLPKHSSWFVHRAGRTARCGREGNALILIASEQLAYVNFLDNHEKVKLDEI--- 385

  Fly   410 EGEQIIKNYQFKMEEVESFRYRAQDCWR----AATRV--------AVHD---------------- 446
               ::..|...|.||:.....:.|...|    |.||.        |.||
 Worm   386 ---KVPTNNSRKSEELRQKMIKIQVSDRAILEAGTRAFVSHVESYAKHDCHLICSLDDLNVVGLA 447

  Fly   447 --------TRIREIK------------IEILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQSHL 491
                    .::||:.            ||....:......|.|:..:...:|:|.:..:..:...
 Worm   448 NSYALLRLPKMRELSQRKDLDMFDRSAIETSEIKYADVKLEANRETVMKEKHEKKVETLAAKDKK 512

  Fly   492 SDMPEYIVPKALKRVVGTSSSPVGASEAKQPRQSAAKAAFERQ--VNDPLMASQVDFGK 548
            ....|   .:.||::.|...:..|.....:.:::..:.|.|..  .||..:..::..||
 Worm   513 RREKE---ARKLKKMGGRFRNGGGTGRKAEEKKALKRKAEEEDDAQNDIRLLKRIKRGK 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	54/189 (29%)
		DEXDc	24..231	CDD:214692	56/200 (28%)
		HELICc	234..386	CDD:238034	37/158 (23%)
ZK512.2	NP_001254980.1	DEADc	17..219	CDD:238167	53/187 (28%)
		DEXDc	24..220	CDD:214692	54/188 (29%)
		HELICc	232..362	CDD:238034	38/160 (24%)
		DUF4217	398..457	CDD:290667	8/58 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010