| Sequence 1: | NP_001285517.1 | Gene: | Hlc / 33118 | FlyBaseID: | FBgn0001565 | Length: | 560 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004930.1 | Gene: | DDX1 / 1653 | HGNCID: | 2734 | Length: | 740 | Species: | Homo sapiens |
| Alignment Length: | 657 | Identity: | 131/657 - (19%) |
|---|---|---|---|
| Similarity: | 205/657 - (31%) | Gaps: | 307/657 - (46%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 11 FHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQ------ 69
Fly 70 -----------------KILNS-KLNASEQYVSAVVLAPTKELCRQSRKVIE------------- 103
Fly 104 ----------------------------------------------------------------- 103
Fly 104 -----------------------------QLVESCGKVVRVADI--------------------- 118
Fly 119 ----------ADSSNDTVTQRHALSESP------------------------------------- 136
Fly 137 ----------------DIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLI 185
Fly 186 KHLPPI------YQAVLVSATL-TDDVVRMKGLCLNNPVTLKLEEPELVPQ-------------D 230
Fly 231 QL------SHQR---ILAEENDKPA------------ILYALLKLRLIR----GKSIIFVNSIDR 270
Fly 271 CYKVRLFLEQFGIR------------ACV-LNSELPANIRIHTISQFNKGTYDIIIASDEHHMEK 322
Fly 323 PGGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFV 387
Fly 388 SMKESKV 394 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hlc | NP_001285517.1 | P-loop_NTPase | 11..220 | CDD:304359 | 78/430 (18%) |
| DEXDc | 24..231 | CDD:214692 | 77/441 (17%) | ||
| HELICc | 234..386 | CDD:238034 | 43/183 (23%) | ||
| DDX1 | NP_004930.1 | Necessary for interaction with RELA. /evidence=ECO:0000269|PubMed:19058135 | 1..525 | 99/529 (19%) | |
| Interaction with dsRNA. /evidence=ECO:0000250|UniProtKB:Q91VR5 | 1..448 | 81/448 (18%) | |||
| Necessary for interaction with HNRNPK. /evidence=ECO:0000269|PubMed:12183465 | 1..295 | 50/294 (17%) | |||
| DEAD-like_helicase_N | 4..>64 | CDD:391939 | 27/59 (46%) | ||
| SPRY_DDX1 | 93..245 | CDD:293933 | 14/155 (9%) | ||
| SrmB | 284..>624 | CDD:223587 | 80/369 (22%) | ||
| DEADc_DDX1 | <288..430 | CDD:350696 | 28/142 (20%) | ||
| DEAD box. /evidence=ECO:0000255|PROSITE-ProRule:PRU00541 | 370..373 | 2/2 (100%) | |||
| Necessary for interaction with HNRNPK. /evidence=ECO:0000269|PubMed:12183465 | 525..740 | 31/127 (24%) | |||
| Necessary for interaction with replicase polyprotein 1ab nsp14 of IBV. /evidence=ECO:0000269|PubMed:20573827 | 536..631 | 30/116 (26%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D973872at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 1.010 | |||||