Protein Alignment slgA and PRODH2

DIOPT Version :10

• Sequence 1: NP_523433.2
• Gene: slgA / 33117
• FlyBaseID: FBgn0003423
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_067055.2
• Gene: PRODH2 / 58510
• HGNCID: 17325
• Length: 460
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 178/571 - (31%)
• Similarity: 267/571 - (46%)
• Gaps: 132/571 - (23%)

  Fly   104 SPAGSPQRDPLDVSFNDPIAAFKSKTTGELIRAYLVYMICSSEKLVEHNMTLMKWSKNVLGQRLF 168
            |.||.|.|....:||:.  .||..|.||||.||.||..:|:...||.|.:.|..||:.:||.||.
Human    10 SQAGPPSRGWQSLSFDG--GAFHLKGTGELTRALLVLRLCAWPPLVTHGLLLQAWSRRLLGSRLS 72

  Fly   169 TLLMKATFYGHFVAGEDQIKIIPTLERLRSFGVKPILDYSVEEDITQEEAEKREVESSVSSAGDK 233
            ...::|:.||.|||||...::...:::||:..::|:|....||          |.:|:..|
Human    73 GAFLRASVYGQFVAGETAEEVKGCVQQLRTLSLRPLLAVPTEE----------EPDSAAKS---- 123

  Fly   234 KEEGSMPQYHVDKSFADRRYKVSSARTYFYLNEATCERNMEIFIKCLEAVSDDDRKAPRAVATGA 298
                                           .||..|.|:...::|::.  ......|.::|..:
Human   124 -------------------------------GEAWYEGNLGAMLRCVDL--SRGLLEPPSLAEAS 155

  Fly   299 TFGTGITAIKLTALGRPQLLLQLSEVIMRTRKYMEDMVGGQGNVLTHHKTIKDLEKYYATLGDNK 363
                 :..:|:|||...:|..:|:..:.|
Human   156 -----LMQLKVTALTSTRLCKELASWVRR------------------------------------ 179

  Fly   364 DVKEFLNNVTSDKEGILHLFPWSGIVDEDSQLSDTFRVPDPQTGQMRRLISQIPPKEEEMFRNMI 428
                                |.:.:.....:|::..     .:||..: :|.:..::.:..|..:
Human   180 --------------------PGASLELSPERLAEAM-----DSGQNLQ-VSCLNAEQNQHLRASL 218

  Fly   429 RRLNTIVKAAADLDVRIMVDAEQTYFQPAISRITLEMMRKYN---KDKAIVFNTYQCYLRETFRE 490
            .||:.:.:.|....||::||||.|...||:|.:...:..::|   :....|:||||..|::||..
Human   219 SRLHRVAQYARAQHVRLLVDAEYTSLNPALSLLVAALAVRWNSPGEGGPWVWNTYQACLKDTFER 283

  Fly   491 VNTDLEQAKRQNFYFGAKLVRGAYMDQERDRAKSLGYPDPVNPTFEATTDMYHRTLSECLRRIKL 555
            :..|.|.|.|....||.|||||||:|:||..|:..|..||..|.:|||:..|.|.|...|..:
Human   284 LGRDAEAAHRAGLAFGVKLVRGAYLDKERAVAQLHGMEDPTQPDYEATSQSYSRCLELMLTHV-- 346

  Fly   556 MKDCDDDAR---KIGIMVASHNEDTVRFAIQQMKEIGISPEDKVICFGQLLGMCDYITFPLGQAG 617
                   ||   ...:|||||||::||.|.::|.|:|| |.|..:||||||||||:::..|||||
Human   347 -------ARHGPMCHLMVASHNEESVRQATKRMWELGI-PLDGTVCFGQLLGMCDHVSLALGQAG 403

  Fly   618 YSAYKYIPYGPVEEVLPYLSRRAQENKGVLKKIKKEKRLLLSEIRRRLMRG 668
            |..||.||||.:|||:|||.||||||:.||:..::|:.||..|:.|||:.|
Human   404 YVVYKSIPYGSLEEVIPYLIRRAQENRSVLQGARREQELLSQELWRRLLPG 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slgA	NP_523433.2	PLN02681	93..668	CDD:215366	177/569 (31%)
PRODH2	NP_067055.2	PLN02681	10..452	CDD:215366	176/567 (31%)