DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slgA and SPCC70.03c

DIOPT Version :9

Sequence 1:	NP_001245796.1	Gene:	slgA / 33117	FlyBaseID:	FBgn0003423	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_588537.1	Gene:	SPCC70.03c / 2539452	PomBaseID:	SPCC70.03c	Length:	492	Species:	Schizosaccharomyces pombe

Alignment Length:	577	Identity:	144/577 - (24%)
Similarity:	227/577 - (39%)	Gaps:	188/577 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 LIRAYLVYMICSSEKLVEHNMTLMKWSKNVLGQRLFTLLMKATFYGHFVAGEDQIKIIPTLERLR 197
            ::|:..||.|||...||:.::..|..........|:....:.|||.||..||....::.|::.|:
pombe    59 VLRSAFVYEICSRAWLVKLSLGAMSLCDVFHLSFLYNPFCRYTFYKHFCGGETPQAVMATMDTLQ 123

  Fly   198 SFGVKPILDYSVEEDI-----TQEEAEKREVESSVSSAGDKKEEGSMPQYHVDKSFADRRYKVSS 257
            :.|:...|:||.|.|:     ..:.|.:..|...|....:|.::       |.:..||:.:
pombe   124 AAGITSCLNYSREVDLDGDMDVNKIASQGVVPPQVPVPSEKNQK-------VLRQIADKAF---- 177

  Fly   258 ARTYFYLNEATCERNMEIFIKCLEAVSDDDRKAPRAVATGATFGTG-ITAIKLTALGRPQLLLQL 321
                        |.||.|.                   ..||:..| :.|:|||....|.:|.:.
pombe   178 ------------ESNMHII-------------------DMATYKPGTVCAVKLTPFINPLVLQRY 211

  Fly   322 SEVIMRTRKYMEDMVGGQGNVLTHHKTIKDLEKYYATLGDNKDVKEFLNNVTSDKEGILHLFPWS 386
            :.::   .:|   .|....|.|.|.|: .:|..|     :..::|:|                |.
pombe   212 NSIL---NQY---PVESACNYLEHLKS-PELSTY-----EVSELKKF----------------WE 248

  Fly   387 GIVDEDSQLSDTFRVPDPQTGQMRRLISQIPPKEEEMFRNMIRRLNTIVKAAADLDVRIMVDAEQ 451
             ..|:..|.:...::|                                          :.:||||
pombe   249 -YADKLCQFAKEKQIP------------------------------------------LFIDAEQ 270

  Fly   452 TYFQPAISRITLEMMRKYNKDKAIVFNTYQCYLRETFREVNTDLEQAKRQNFYFGAKLVRGAYMD 516
            ||||..:..:|:::||||||:.|||.||||.||:::.:.::..:::...:.:..|||||||||::
pombe   271 TYFQDCMHAVTVDLMRKYNKEVAIVHNTYQLYLKKSRKIMDDHIKKCVAEGWLMGAKLVRGAYLN 335

  Fly   517 QERDRAKSLGYPDPVNPTFEATTDMYHRTLSECLRRIKLMKDCDDDARKI--------------- 566
            .|              |.|     :.|.|.:|      ..||.|.....|
pombe   336 SE--------------PRF-----LIHDTKAE------TDKDFDSAVEAIIAAAAKFAPGDPASA 375

  Fly   567 -----------GIMVASHNEDTVRFAIQQMKEIGISPEDKV------ICFGQLLGMCDYITFPLG 614
                       ||||||||:.|:      .:.:.::...||      ....|||||.|.||:.|.
pombe   376 SDPIASRKGKWGIMVASHNKKTM------FESVNLAETKKVDFTKTSFYLAQLLGMADDITYALA 434

  Fly   615 ------QAGYSAYKYIPYGPVEEVLPYLSRRAQENKGVLKKIKKEKRLLLSEIRRRL 665
                  |..:...||:..||:.||||||.|||:||...|.:.|:|:......:|||:
pombe   435 YSQRNQQPNFCIVKYVSCGPISEVLPYLVRRARENIDALDRCKEERAYYRQALRRRI 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slgA	NP_001245796.1	PLN02681	93..668	CDD:215366	144/577 (25%)
slgA	NP_001245796.1	Pro_dh	417..653	CDD:279895	81/273 (30%)
SPCC70.03c	NP_588537.1	PutA	35..486	CDD:223580	141/570 (25%)
SPCC70.03c	NP_588537.1	Pro_dh	<251..469	CDD:279895	80/290 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	119	1.000	Domainoid score	I1477
eggNOG	1	0.900	-	-		E1_COG0506
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I1173
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001607
OrthoInspector	1	1.000	-	-		oto100679
orthoMCL	1	0.900	-	-		OOG6_101295
Panther	1	1.100	-	-	LDO	PTHR13914
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R983
SonicParanoid	1	1.000	-	-		X1170
TreeFam	1	0.960	-	-
	12	11.850