Protein Alignment Sep1 and CDC12

DIOPT Version :9

• Sequence 1: NP_523430.1
• Gene: Sep1 / 33114
• FlyBaseID: FBgn0011710
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_011975.1
• Gene: CDC12 / 856507
• SGDID: S000001149
• Length: 407
• Species: Saccharomyces cerevisiae
• Alignment Length: 393
• Identity: 147/393 - (37%)
• Similarity: 228/393 - (58%)
• Gaps: 51/393 - (12%)

  Fly    13 PGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERIIPDAIEKQKQTV 77
            |..||.:|||||.::...::|..||:|:.|||||||:|.:|:||.|.|..........|..::||
Yeast    12 PPPVGISNLPNQRYKIVNEEGGTFTVMLCGESGLGKTTFINTLFQTVLKRADGQQHRQEPIRKTV 76

  Fly    78 KLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLNRRNIVDN 142
            :::.:...:||:..:||:.|:|||||||.::|:.::..::::||:|::.::|.|....|....|.
Yeast    77 EIDITRALLEEKHFELRVNVIDTPGFGDNVNNNKAWQPLVDFIDDQHDSYMRQEQQPYRTKKFDL 141

  Fly   143 RIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQEIESHGIK 207
            |:|...|||.|.||||||:|:|.||:|.::.|::|||||||.||.:|:.:.|.||.|.||:..|:
Yeast   142 RVHAVLYFIRPTGHGLKPIDIETMKRLSTRANLIPVIAKADTLTAQELQQFKSRIRQVIEAQEIR 206

  Fly   208 IYPLPDCDSDEDEDYK----------EQVKQLKEAVPFAVCGANTLLE-VKGKKVRGRLYPWGVV 261
            |: .|..|:|..||.|          |..:||.||:|||:.|:....: .:|.:|..|.||||:|
Yeast   207 IF-TPPLDADSKEDAKSGSNPDSAAVEHARQLIEAMPFAIVGSEKKFDNGQGTQVVARKYPWGLV 270

  Fly   262 EVENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRL------AKG-------------- 305
            |:||..||||.|||.:|: |::.||...|||:|||.||..||      .:|
Yeast   271 EIENDSHCDFRKLRALLLRTYLLDLISTTQEMHYETYRRLRLEGHENTGEGNEDFTLPAIAPARK 335

  Fly   306 ------IKGKENG--------VKAERDSSSQVVSNSVLGEKDRI---LQEKEAELRRMQEMLAQM 353
                  .|.:||.        ||||.....|...| ::.|:.|:   |:|.:.::::::|.:..:
Yeast   336 LSHNPRYKEEENALKKYFTDQVKAEEQRFRQWEQN-IVNERIRLNGDLEEIQGKVKKLEEQVKSL 399

  Fly   354 QAR 356
            |.:
Yeast   400 QVK 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	145/377 (38%)
		Septin	32..304	CDD:279124	123/289 (43%)
CDC12	NP_011975.1	CDC3	16..404	CDD:227352	145/389 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	233	1.000	Domainoid score	I399
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51878
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	1	1.000	-	-		X204
TreeFam	1	0.960	-	-
	9	8.910