Protein Alignment Sep1 and Septin12

DIOPT Version :9

• Sequence 1: NP_523430.1
• Gene: Sep1 / 33114
• FlyBaseID: FBgn0011710
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: XP_006522640.1
• Gene: Septin12 / 71089
• MGIID: 1918339
• Length: 362
• Species: Mus musculus
• Alignment Length: 313
• Identity: 144/313 - (46%)
• Similarity: 207/313 - (66%)
• Gaps: 27/313 - (8%)

  Fly     8 SSIETP-----GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLY----PE 63
            ||..||     |.||...:.:|:..|::|.||||.:||||:|||||||:||:||.:.::    |.
Mouse    15 SSPRTPPNEMFGPVGIEAVLDQLRIKAMKTGFEFNIMVVGQSGLGKSTMVNTLFKSKVWQSTEPN 79

  Fly    64 RIIPDAIEKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFL 128
            ..:|     ..||::|.:.|..|||:|:||:|||.|||||||.|:|...:..||.||::|||::|
Mouse    80 LDVP-----MPQTLELHSVTHVIEEKGLKLKLTVTDTPGFGDQINNDKCWDPILSYINQQYEQYL 139

  Fly   129 RDESGLNR-RNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILR 192
            ::|..:.| |:|.|.|:|||.||:.|.||.|:|||:||:::|...||:|||||:||.||.:|...
Mouse   140 QEELLITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLRRLCRTVNVVPVIARADSLTIEERDA 204

  Fly   193 LKCRIMQEIESHGIKIYPLPDCDSDEDEDYKEQV--KQLKEAVPFAVCGANTLLEVKGKKVRGRL 255
            .:.||.|.:::|.|.:|| ..|   .|||..:::  .:::|.:||||.||:....|.|:.|.||.
Mouse   205 FRSRIQQNLKTHCIDVYP-QKC---FDEDVNDRLLNSKIREQIPFAVVGADREHIVNGRCVLGRK 265

  Fly   256 YPWGVVE-----VENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRL 302
            ..||::|     |||..||:|:.||.:|| :|:|||:::|..|||||||..||
Mouse   266 TKWGIIEGPCLAVENMAHCEFLLLRDLLIRSHLQDLKDITHNVHYENYRVLRL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	141/308 (46%)
		Septin	32..304	CDD:279124	134/284 (47%)
Septin12	XP_006522640.1	CDC_Septin	45..320	CDD:206649	134/283 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838868
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.780