DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sep1 and septin12

DIOPT Version :9

Sequence 1:	NP_523430.1	Gene:	Sep1 / 33114	FlyBaseID:	FBgn0011710	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	XP_031748559.1	Gene:	septin12 / 594940	XenbaseID:	XB-GENE-5894593	Length:	892	Species:	Xenopus tropicalis

Alignment Length:	311	Identity:	153/311 - (49%)
Similarity:	212/311 - (68%)	Gaps:	17/311 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLY---PERIIPDAIEK 72
            |..||||...:.:|:.||::|.||||.:||||:||||||||||:||.:.:.   |...||
Frog   590 EPIGYVGIDAVLDQMRRKAMKNGFEFNIMVVGQSGLGKSTLVNTLFKSKVIRKSPGATIP----- 649

  Fly    73 QKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLNR- 136
              :||:|.|.:..:||||:::||||:|||||||.|:|.|.:..|::||.||||::||:|..:||
Frog   650 --KTVELNAVSQVVEERGMEMRLTVIDTPGFGDQINNQNCWDPIIKYIHEQYEKYLREEILINRK 712

  Fly   137 RNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQEI 201
            |.|.|:|||.|.|||.|.||.|:|||:||||:|...||:||||||||.||.:|....|.||.:::
Frog   713 RRIPDSRIHSCIYFIPPTGHWLRPLDLEFMKRLGRIVNVVPVIAKADTLTLEEREEFKQRIRKDL 777

  Fly   202 ESHGIKIYPLPDCDSDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEVENP 266
            ::|||.:||.|:.|.|..:.....  :::|.:||||.|.:...:|.|:||.||...|||:||||.
Frog   778 QTHGISVYPQPELDEDPVDALVND--KIREKIPFAVVGTDEEHQVNGRKVLGRKTKWGVIEVENT 840

  Fly   267 DHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAKGIKG---KENGV 313
            .||:|..||.:|| :::|||:::|..:|||.||..||.:..:.   ||.||
Frog   841 AHCEFANLRDLLIRSNLQDLKDITHNIHYETYRVSRLNEKFQSSQTKEVGV 891

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	152/309 (49%)
Sep1	NP_523430.1	Septin	32..304	CDD:279124	140/276 (51%)
septin12	XP_031748559.1	PRK10263	<231..>401	CDD:236669
septin12	XP_031748559.1	CDC_Septin	611..881	CDD:206649	140/278 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920