DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sep1 and Septin6

DIOPT Version :9

Sequence 1:NP_523430.1 Gene:Sep1 / 33114 FlyBaseID:FBgn0011710 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_001170795.1 Gene:Septin6 / 56526 MGIID:1888939 Length:434 Species:Mus musculus


Alignment Length:350 Identity:151/350 - (43%)
Similarity:218/350 - (62%) Gaps:32/350 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 SIETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERIIPDAIEKQ 73
            ::...|:|||.:||:|:..|||.:||.|.::.|||:|||||||:::||.|....|    .|...|
Mouse    16 TVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE----PATHTQ 76

  Fly    74 KQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLNR-- 136
             ..|:|:::|.:::|..|.|:||:|.|.||||.|:..:|:..|:|:||.|:|.:|::|..:.|  
Mouse    77 -PGVQLQSNTYDLQESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVL 140

  Fly   137 RNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQEI 201
            .:..|:|||.|.|||:|.||.||.||:..||||.|||||:|||||:|.::|.|:.:.|.:|..|:
Mouse   141 HSYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSEL 205

  Fly   202 ESHGIKIYPLPDCDSDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEVENP 266
            .|:|::||..|    .:||...|....:...:||||.|:...:::..|.:|.|.||||.|:|||.
Mouse   206 VSNGVQIYQFP----TDDESVSEINGTMNAHLPFAVVGSTEEVKIGNKMMRARQYPWGTVQVENE 266

  Fly   267 DHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAKGIKGKENGVKAERDSSSQVVS----- 325
            .||||:|||.||| .:|:||:|.|...|||.||..:|      :|.|.| :.|..|:..|     
Mouse   267 AHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKL------EEMGFK-DTDPDSKPFSLQETY 324

  Fly   326 ----NSVLGEKDRILQEKEAELRRM 346
                |..|||    ||:||.|:|:|
Mouse   325 EAKRNEFLGE----LQKKEEEMRQM 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sep1NP_523430.1 CDC3 13..342 CDD:227352 148/340 (44%)
Septin 32..304 CDD:279124 124/274 (45%)
Septin6NP_001170795.1 CDC3 21..373 CDD:227352 150/344 (44%)
CDC_Septin 39..307 CDD:206649 125/282 (44%)
G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056 49..56 5/6 (83%)
G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056 101..104 1/2 (50%)
G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056 184..187 2/2 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 403..434
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5019
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D845354at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2060
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.850

Return to query results.
Submit another query.