Protein Alignment Sep1 and SEPTIN11

DIOPT Version :9

• Sequence 1: NP_523430.1
• Gene: Sep1 / 33114
• FlyBaseID: FBgn0011710
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001293076.1
• Gene: SEPTIN11 / 55752
• HGNCID: 25589
• Length: 439
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 151/350 - (43%)
• Similarity: 218/350 - (62%)
• Gaps: 32/350 - (9%)

  Fly     9 SIETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERIIPDAIEKQ 73
            ::...|:|||.:||:|:..||..:||.|.::.|||:|:|||||:::||.|     :...|.....
Human    25 NLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNT-----KFESDPATHN 84

  Fly    74 KQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLNRR- 137
            :..|:|:|.:.|::|..|:|:||:|||.||||.|:..:|:..|:||||.|:|.:|::|..:.|.
Human    85 EPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSL 149

  Fly   138 -NIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQEI 201
             |..|.|||.|.|||:|.||.||.||:..||||.|||||:|:|||||.:.|.|:.:.|.:||.|:
Human   150 FNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSEL 214

  Fly   202 ESHGIKIYPLPDCDSDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEVENP 266
            .|:|::||..|    .::|...|....:...:||||.|:...:::..|..:.|.||||||:|||.
Human   215 VSNGVQIYQFP----TDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENE 275

  Fly   267 DHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAKGIKGKENGVKAERDSSSQVVS----- 325
            :||||:|||.||| .:|:||:|.|...|||.||..:|      :|.|.| :.|..|:..|
Human   276 NHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKL------EEMGFK-DTDPDSKPFSLQETY 333

  Fly   326 ----NSVLGEKDRILQEKEAELRRM 346
                |..|||    ||:||.|:|:|
Human   334 EAKRNEFLGE----LQKKEEEMRQM 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	148/340 (44%)
		Septin	32..304	CDD:279124	125/274 (46%)
SEPTIN11	NP_001293076.1	CDC_Septin	48..316	CDD:206649	126/282 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.780