DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sep1 and sept9a

DIOPT Version :9

Sequence 1:	NP_523430.1	Gene:	Sep1 / 33114	FlyBaseID:	FBgn0011710	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_944593.1	Gene:	sept9a / 337243	ZFINID:	ZDB-GENE-030131-9187	Length:	584	Species:	Danio rerio

Alignment Length:	321	Identity:	141/321 - (43%)
Similarity:	221/321 - (68%)	Gaps:	11/321 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IETP----GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERIIPDAI 70
            :|.|    .|||...:..|:.||::|:|||..:||||:||||||||:|:||.:.:..:..:..|.
Zfish   268 LEKPSIDFSYVGIDAILEQMRRKAMKQGFELNIMVVGQSGLGKSTLMNTLFKSKVSRKSFMGTAE 332

  Fly    71 EKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLN 135
            ||..:|:::::.:.:|||:||:::|||:|||||||.|:|.|.:..|:::|::|||::|::|..::
Zfish   333 EKIPKTIEIKSVSHDIEEKGVRMKLTVIDTPGFGDQINNENCWQPIMKFINDQYEQYLQEEINID 397

  Fly   136 R-RNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQ 199
            | :.|.::|:|||.|||.|.||.|:|||||||::|...|||||||||||.||.:|....|.:|.:
Zfish   398 RKKRIPESRVHCCIYFIPPTGHCLRPLDVEFMRRLSKVVNIVPVIAKADTLTLEERDFFKKKIRE 462

  Fly   200 EIESHGIKIYPLPDCDSD-EDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEV 263
            |:.::||.:||..:.|.| ||....|::   :|.:||||.|::...:|.|:::.||...||.:||
Zfish   463 ELRANGIDVYPQKEFDEDAEDRMINEKI---REMIPFAVVGSDQEYQVNGRRLLGRKTKWGTIEV 524

  Fly   264 ENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAKGIKGKENGVKAERDSSSQV 323
            ||..||:|..||.:|| ||||:::::|..:|||.||..||.:. ..:.||:.....:|.::
Zfish   525 ENIAHCEFAYLRDLLIRTHMQNIKDITSSIHYEMYRVRRLNEN-NTQANGLADHHPASHEI 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	140/318 (44%)
Sep1	NP_523430.1	Septin	32..304	CDD:279124	129/274 (47%)
sept9a	NP_944593.1	CDC3	276..>570	CDD:227352	136/297 (46%)
sept9a	NP_944593.1	CDC_Septin	294..568	CDD:206649	129/277 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950