Protein Alignment Sep1 and SEPTIN6

DIOPT Version :9

• Sequence 1: NP_523430.1
• Gene: Sep1 / 33114
• FlyBaseID: FBgn0011710
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: XP_011529619.1
• Gene: SEPTIN6 / 23157
• HGNCID: 15848
• Length: 526
• Species: Homo sapiens
• Alignment Length: 354
• Identity: 153/354 - (43%)
• Similarity: 220/354 - (62%)
• Gaps: 32/354 - (9%)

  Fly     5 KGFSSIETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERIIPDA 69
            :|..::...|:|||.:||:|:..|||.:||.|.::.|||:|||||||:::||.|....|    .|
Human    12 EGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE----PA 72

  Fly    70 IEKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGL 134
            ...| ..|:|:::|.:::|..|:|:||:|.|.||||.|:..:|:..|:|:||.|:|.:|::|..:
Human    73 THTQ-PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

  Fly   135 NR--RNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRI 197
            .|  ....|:|||.|.|||:|.||.||.||:..||||.|||||:|:|||||.::|.|:.:.|.:|
Human   137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKI 201

  Fly   198 MQEIESHGIKIYPLPDCDSDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVE 262
            ..|:.|:|::||..|    .:||...|....:...:||||.|:...|::..|.:|.|.||||.|:
Human   202 TSELVSNGVQIYQFP----TDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRARQYPWGTVQ 262

  Fly   263 VENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAKGIKGKENGVKAERDSSSQVVS- 325
            |||..||||:|||.||| .:|:||:|.|...|||.||..:|      :|.|.| :.|..|:..|
Human   263 VENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKL------EEMGFK-DTDPDSKPFSL 320

  Fly   326 --------NSVLGEKDRILQEKEAELRRM 346
                    |..|||    ||:||.|:|:|
Human   321 QETYEAKRNEFLGE----LQKKEEEMRQM 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	149/340 (44%)
		Septin	32..304	CDD:279124	125/274 (46%)
SEPTIN6	XP_011529619.1	CDC3	21..373	CDD:227352	152/345 (44%)
		CDC_Septin	39..307	CDD:206649	126/282 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850