Protein Alignment Sep1 and SEPTIN10

DIOPT Version :9

• Sequence 1: NP_523430.1
• Gene: Sep1 / 33114
• FlyBaseID: FBgn0011710
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001308427.1
• Gene: SEPTIN10 / 151011
• HGNCID: 14349
• Length: 544
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 155/381 - (40%)
• Similarity: 232/381 - (60%)
• Gaps: 40/381 - (10%)

  Fly     9 SIETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLT---DLYPERIIPDAI 70
            |:...|:|||.:||:|:..:|:::||.|.::.|||:|:|||||:::||.|   |.......|:
Human    40 SLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPN-- 102

  Fly    71 EKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLN 135
                  |||:|.|.|::|..|:|:||:|:|.||||.|:...|:..|::|||.|:|.:|::|..:.
Human   103 ------VKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIK 161

  Fly   136 RRNIV--DNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIM 198
            |....  |:|||.|.|||||.||.||.||:..||.|.|||||:|||||||.::|.|:.:.|.::|
Human   162 RSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLM 226

  Fly   199 QEIESHGIKIYPLPDCDSDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEV 263
            .|:.|:|::||..|   :|:|...|... .:...:||||.|:...::|..|.|:.|.||||||:|
Human   227 SELVSNGVQIYQFP---TDDDTIAKVNA-AMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQV 287

  Fly   264 ENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAK-GIK--GKEN------------- 311
            ||.:||||:|||.||| |:|:||:|.|...|||.||..:|.: |..  |.||
Human   288 ENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKR 352

  Fly   312 ----GVKAERDSSSQVVSNSVLGEKDRILQEKEAELRRMQEMLAQM--QARMQAQQ 361
                |.:..::...:.:....:.||:.||:|.|.||:...|.|.::  :.||:.::
Human   353 HEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	148/354 (42%)
		Septin	32..304	CDD:279124	129/277 (47%)
SEPTIN10	NP_001308427.1	CDC3	44..397	CDD:227352	152/364 (42%)
		CDC_Septin	63..331	CDD:206649	129/279 (46%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	73..80		4/6 (67%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	125..128		1/2 (50%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	208..211		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850