Protein Alignment Sep1 and Septin10

DIOPT Version :9

• Sequence 1: NP_523430.1
• Gene: Sep1 / 33114
• FlyBaseID: FBgn0011710
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001365992.1
• Gene: Septin10 / 103080
• MGIID: 1918110
• Length: 456
• Species: Mus musculus
• Alignment Length: 382
• Identity: 150/382 - (39%)
• Similarity: 234/382 - (61%)
• Gaps: 42/382 - (10%)

  Fly     9 SIETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLT---DLYPERIIPDAI 70
            |:...|:|||.:||:|:..:|:::||.|.::.|||:|:|||||:|:||.|   :|......|
Mouse    17 SLSMCGHVGFESLPDQLVDRSIEQGFCFNILCVGETGIGKSTLINTLFNTNFEELESSHFCP--- 78

  Fly    71 EKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLN 135
                 .|:|.|.|.|::|..|:|:||:|:|.||||.|:..:|:..|::|||:|:|.:|::|..:.
Mouse    79 -----CVRLRAQTYELQESNVRLKLTIVNTVGFGDQINKEDSYQPIVDYIDDQFEAYLQEELKIK 138

  Fly   136 RR--NIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIM 198
            |.  |..|:|||.|.|||:|.||.|:.||:..||.|.:||||:|:|||||.::|.|:.:.|.::|
Mouse   139 RALFNYHDSRIHVCLYFIAPTGHSLRTLDLLTMKSLDNKVNIIPLIAKADTISKSELQKFKMKLM 203

  Fly   199 QEIESHGIKIYPLPDCDSDEDEDYKEQVK-QLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVE 262
            .|:..:|::||..|     .|:|...::. .:...:||||.|:...::|..|.|:||.||||:|:
Mouse   204 NELVINGVQIYQFP-----TDDDTTSKINGAMNGHLPFAVVGSMDEIKVGNKMVKGRQYPWGIVQ 263

  Fly   263 VENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAK-GI--KGKEN------------ 311
            |||.:||||:|||.||| |:|:||:|.|...|||.||..:|.: |.  .|.||
Mouse   264 VENENHCDFVKLREMLICTNMEDLREQTHMRHYELYRRCKLQEMGFVDMGPENKPLSLQETYEAK 328

  Fly   312 -----GVKAERDSSSQVVSNSVLGEKDRILQEKEAELRRMQEMLAQM--QARMQAQQ 361
                 |.:..::...:.:....:.||:.||:|.|.||:...|.|.::  :.||:.::
Mouse   329 RHEFYGERQRKEEQMKQMFVQRVKEKEAILKEAERELQAKFEHLKRIHQEERMKLEE 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep1	NP_523430.1	CDC3	13..342	CDD:227352	143/355 (40%)
		Septin	32..304	CDD:279124	124/278 (45%)
Septin10	NP_001365992.1	CDC_Septin	40..308	CDD:206649	124/280 (44%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	50..57		4/6 (67%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	102..105		1/2 (50%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	185..188		2/2 (100%)
		PTZ00121	<274..426	CDD:173412	35/112 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850