Protein Alignment peng and pum3

DIOPT Version :10

• Sequence 1: NP_523429.1
• Gene: peng / 33112
• FlyBaseID: FBgn0015527
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001340777.1
• Gene: pum3 / 553068
• ZFINID: ZDB-GENE-050506-149
• Length: 629
• Species: Danio rerio
• Alignment Length: 724
• Identity: 188/724 - (25%)
• Similarity: 328/724 - (45%)
• Gaps: 126/724 - (17%)

  Fly    26 GKRAN-GQKFKPGG-AGGARKFDKFGGGAGKSFVKPGA-GGAKKFDKSGPGGFKKFDKSGATGDK 87
            ||:.: ..|.|||| ..|.|.|.......||.|.|.|. ||.:||::....|  ||.|      |
Zfish    15 GKKPSFKSKGKPGGKPQGKRPFKPHNNDKGKGFRKSGGEGGPQKFNRKPTDG--KFAK------K 71

  Fly    88 RLGGNKFRGKPQTQPQAPAEGEKQDWNKFKKEKKDLKLKRKSA--KDTYEISKEANQIHEKLR-- 148
            |    ||.|....|.:.. |.:|..|::||::||:|||.|:..  |::|:|...|.|:.|.:|
Zfish    72 R----KFPGDRIKQEEGD-ERKKPKWDEFKQKKKELKLNRQQTDRKESYQIVSRAKQVWEMVRRK 131

  Fly   149 -CRRTENKDKLVEQIYKVLNVGDTISKVVKAHDTARVIQSMLKYASPALRAEISEKLLPFTVEMC 212
             |.: :.:.||::::..:  |...|..:..|||:.||:|..:::.|...|.|:.::|....||:.
Zfish   132 DCDK-QKRTKLMKELQDL--VKGKIKTIAFAHDSTRVLQCFIQFGSDKQRKEVFDELKEHIVELS 193

  Fly   213 QSKYAQFCVQRMLKYGAPATKAKLVDSLYGHIVRLAGHSIGSGLLDSMY-QSATPNQRIYMRQEF 276
            :||||:..|::.|.||:.....:::.:..|.:.::..||..|.:::..| ..|..:||:.:.:|.
Zfish   194 KSKYARNIVKKFLMYGSKEQVGEVMLAFKGKVRQMLRHSEASSVVEYAYNDKAILSQRLMLTEEL 258

  Fly   277 YGDLYRKAKDSNVKTLSDTYKEATNMKASILGSVKANLDHVANKQ-LVDSALVHAVMLEYLRACD 340
            ||:.:...|.|...||....:.......|||..:|..|..:|.|: ::..:|||.|.|::.....
Zfish   259 YGNTFTVLKSSVCPTLEKVLEANPGKLESILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFEHAP 323

  Fly   341 EDEEKLEETVTAFAALVPHMLSTKEGSEAAVICFYKSTPKNRRAIIKNIKEHLLKIANHEHGHVF 405
            :.:.  .|.:.:....|.:|..|.:|:...:.|.:..|.|:|:.|:|.:|.::.|.|..|:.|:.
Zfish   324 DKQR--TEMIESIREAVVYMAHTHDGARVTMHCLWHGTTKDRKVIVKTMKSYIAKFAMGEYAHLV 386

  Fly   406 LISLLNALDDTKATKKAIYDHLHGDLKALMSSPYGRRVIQWLVAPGDTTCFHPEFIRTVE--EGL 468
            |::..:.:||||..|:.|...:...|..::|:.:|::|:.:|::|.|.....||.|:.:|  :|.
Zfish   387 LLAAFDCIDDTKLVKQIIISEMVSSLSEIISNKHGKKVLLYLLSPRDPAHLLPEIIQVLEKGDGN 451

  Fly   469 AFGKKEKELRRKEILEQIEAPIAQSIAEDAAFWLSNSHIGLVTGDILNHIQGESYEKAASALAQV 533
            |..||:..:||||:||.....:...:.|:|...:.:....:|..|||           .||:
Zfish   452 AHSKKDVLIRRKELLEAASPSLLNHLCENAQSMVMDKSCCVVVSDIL-----------GSAV--- 502

  Fly   534 VVQPEWRISADAAGPQPQDKKKPHNDVEAIIAQATKQRRKLLYVESSSDDEDEDEDEDEESDDEG 598
                                                                            |
Zfish   503 ----------------------------------------------------------------G 503

  Fly   599 DEKEQKEAAADDAEPKVKKAKKEPKKPKAKEEEPAAPLVSGIEEAGMHIVLKKILKNDGKREGTP 663
            |.:...||.|..|:..:....|:.:...|  |.||.           |:|||.:::.|.|.:.|.
Zfish   504 DLRPAMEAVAALADGPLIPGGKDGQLHMA--EHPAG-----------HLVLKWLIEQDTKMKDTE 555

  Fly   664 ----FSQQLLQNLSSDVLKAWLGVNRACFVLLKLVEECPALLDDCKKAIAAERSLSQILADRKTP 724
                ||:.||:.:..:.||.|..|||...:|..|::.....:.:..||: .:.|:.::...:.:.
Zfish   556 REERFSRILLEKVGLENLKTWASVNRGAIILCCLLQSADESVAEEVKAM-LKSSIPELQRLQNSK 619

  Fly   725 GAKLLAAKL 733
            |.::|..||
Zfish   620 GIEVLLEKL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
peng	NP_523429.1	Pumilio	<183..>254	CDD:480718	20/70 (29%)
		Pumilio	438..>537	CDD:480718	27/100 (27%)
pum3	NP_001340777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		31/89 (35%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q15397	88..100		4/11 (36%)
		Pumilio 1. /evidence=ECO:0000250|UniProtKB:Q15397	160..195		11/34 (32%)
		Pumilio	165..425	CDD:480718	69/261 (26%)
		Pumilio 2. /evidence=ECO:0000250|UniProtKB:Q15397	196..231		8/34 (24%)
		Pumilio 3. /evidence=ECO:0000250|UniProtKB:Q15397	232..260		7/27 (26%)
		Pumilio 4. /evidence=ECO:0000250|UniProtKB:Q15397	272..308		9/35 (26%)
		Pumilio 5. /evidence=ECO:0000250|UniProtKB:Q15397	309..344		8/36 (22%)
		Pumilio 6. /evidence=ECO:0000250|UniProtKB:Q15397	345..380		10/34 (29%)
		Pumilio 7. /evidence=ECO:0000250|UniProtKB:Q15397	381..418		10/36 (28%)
		CPL	418..553	CDD:462370	44/225 (20%)
		Pumilio 8. /evidence=ECO:0000250|UniProtKB:Q15397	419..487		21/67 (31%)
		Pumilio 9. /evidence=ECO:0000250|UniProtKB:Q15397	488..534		14/125 (11%)
		Pumilio 10. /evidence=ECO:0000250|UniProtKB:Q15397	535..579		16/54 (30%)
		Pumilio 11. /evidence=ECO:0000250|UniProtKB:Q15397	580..618		7/38 (18%)