Protein Alignment peng and Pum3

DIOPT Version :9

• Sequence 1: NP_523429.1
• Gene: peng / 33112
• FlyBaseID: FBgn0015527
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_803425.1
• Gene: Pum3 / 52874
• MGIID: 106253
• Length: 648
• Species: Mus musculus
• Alignment Length: 744
• Identity: 184/744 - (24%)
• Similarity: 325/744 - (43%)
• Gaps: 158/744 - (21%)

  Fly     7 KGPANVANTASPLKAHESSGKRANGQKFKPGGAGGARKFDKFGGGAGKSFVKPGAGGAKKFDKSG 71
            |...:.::...|.||.:..|.:...:.|:.|.                  .|||..|.|:| |:.
Mouse    26 KNSESSSSKTFPRKAVKEGGPKVTSKNFEKGA------------------TKPGKKGVKQF-KNK 71

  Fly    72 PGGFK----KFDKSGATGDKRLGGNKFRGKPQTQPQAPAE---GEKQDWNKFKKEKKDLKLKRK- 128
            |.|.|    ||.|:          |||..|.:.||...::   .:|..|:.|||:||:||..|:
Mouse    72 PQGGKGPKDKFQKA----------NKFSKKRKFQPDGESDESGAKKPKWDDFKKKKKELKQSRQL 126

  Fly   129 SAKDTYEISKEANQIHEKLR---CRRTENKDKLVEQIYKVLNVGDTISKVVKAHDTARVIQSMLK 190
            |.|..|:|...|..|.|.||   |.: |.:.||:..:.|::.  ..|..:..|||:.||||..::
Mouse   127 SDKTNYDIVVRAKHIWESLRRKDCDK-EKRVKLMSDLQKLIQ--GKIKTIAFAHDSTRVIQCFIQ 188

  Fly   191 YASPALRAEISEKLLPFTVEMCQSKYAQFCVQRMLKYGAPATKAKLVDSLYGHIVRLAGHSIGSG 255
            |.:...|.:..::|....||:.::||::..|::.|.||:....|:::.|..||:.::..||..|.
Mouse   189 YGNEEQRKQAFQELQGDLVELSKAKYSRNIVKKFLMYGSKPQVAEIIRSFKGHVRKMLRHSEASA 253

  Fly   256 LLDSMY-QSATPNQRIYMRQEFYGDLYRKAKDSNVKTLSDTYKEATNMKASILGSVKANLDHVAN 319
            :::..| ..|...||..:.:|.||:.::..|.::..||....:........|:..:|..|..:|.
Mouse   254 IVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHPTLDKVLELQPAKLELIMDEMKQILTPMAQ 318

  Fly   320 KQ-LVDSALVHAVMLEYLRACDEDEEKLEETVTAFAALVPHMLSTKEGSEAAVICFYKSTPKNRR 383
            |: ::..:|||.|.|::....  ..:...|.:.|....|.::..|.:|:..|:.|.:..|||:|:
Mouse   319 KEAVIKHSLVHKVFLDFFTYA--PPKPRSELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRK 381

  Fly   384 AIIKNIKEHLLKIANHEHGHVFLISLLNALDDTKATKKAIYDHLHGDLKALMSSPYGRRVIQWLV 448
            .|:|.:|.::.|:||.::.|:.|::..:.:||||..|:.|...:...|.::::..|||:|:.:|:
Mouse   382 VIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLM 446

  Fly   449 APGDTTCFHPEFIRTVE--EGLAFGKKEKELRRKEILEQIEAPIAQSIAEDAAFWLSNSHIGLVT 511
            :|.|.....||.|..::  :|.|..||:..:||:|:||.|...
Mouse   447 SPRDPAHTVPELIELLQKGDGNAHSKKDTAIRRRELLESISPA---------------------- 489

  Fly   512 GDILNHIQGESYEKAASALAQVVVQPEWRISADAAGPQPQDKKKPHNDVEAIIAQATKQRRKLLY 576
              :|:::||.:.|......|.|:|..                         ::..||
Mouse   490 --LLSYLQGHTQEVVLDKSACVLVSD-------------------------MLGSAT-------- 519

  Fly   577 VESSSDDEDEDEDEDEESDDEGDEKEQKEAAADDAEPKVKKAKKEPKKPKAKEEEPAAPLVSGIE 641
                                 ||.:...:|.|..|..::....|:.:...|  |.||.
Mouse   520 ---------------------GDVQPAMDAIASLAAAELHPGGKDGELHVA--EHPAG------- 554

  Fly   642 EAGMHIVLKKILKNDGK-----REGTPFSQQLLQNLSSDVLKAWLGVNRACFVLLKLVEEC---- 697
                |:|||.:|:.|.|     :||. |::.|::.:....||:|..:||...:|..|::.|
Mouse   555 ----HLVLKWLLEQDKKMKESGKEGC-FAKTLVERVGMKNLKSWASINRGAIILSSLLQSCDQEV 614

  Fly   698 --------PALLDDCKKAIAAERSLSQIL 718
                    ..|:...:|..::.|.:..:|
Mouse   615 VNKVKGGLKPLIPTLEKNKSSSRGIQTLL 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
peng	NP_523429.1	Pumilio	<183..>254	CDD:277559	21/70 (30%)
		CPL	438..>537	CDD:285370	27/100 (27%)
Pum3	NP_803425.1	Pumilio	182..387	CDD:356422	54/206 (26%)
		CPL	434..571	CDD:369709	46/227 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837144
Domainoid	1	1.000	171	1.000	Domainoid score	I3742
eggNOG	1	0.900	-	-		E1_KOG2050
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	211	1.000	Inparanoid score	I3652
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55991
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004242
OrthoInspector	1	1.000	-	-		oto93784
orthoMCL	1	0.900	-	-		OOG6_102938
Panther	1	1.100	-	-	LDO	PTHR13389
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1033
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.790